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Gender Difference in CT-Measured Emphysema Identified

A new study reveals that in men with chronic obstructive pulmonary disease (COPD), at all stages of severity, men have more CT-measurable emphysema than women with COPD.

The study, conducted by researchers from the University of Alabama, the Birmingham VA Medical Center, and Brigham and Women’s Hospital, classified the COPD stages of 396 current and former smokers enrolled in the National Lung Screening Trial. Subjects participated in spirometry testing and a CT exam, which were then analyzed to determine regional and total emphysema. Current and former male smokers were found to have more extensive CT emphysema at all levels of disease severity than females. Researchers hope this may help to explain gender differences in the presentation and natural history of COPD. This study appears in the August issue of CHEST, the peer-reviewed journal of the American College of Chest Physicians. -American College of Chest Physicians

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