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Interior Ministry spokesman Zemarai Bashari said both police and civilians are among the dead and wounded. A correspondent for RFE/RL's Radio Free Afghanistan quotes officials as saying the death toll could be higher.
Police say the suicide bomber was wearing a police uniform, which allowed him to gain access to the bus.
A purported Taliban spokesman, Zabillah Mujahid, claimed responsibility for the attack.
The attack is the second suicide bombing targeting Afghan security forces in the past four days. On September 29, a similar attack against an Afghan Army bus in Kabul killed 30 people, mostly soldiers.
Copyright (c) 2006. RFE/RL, Inc. Reprinted with the permission of Radio Free Europe/Radio Liberty, 1201 Connecticut Ave., N.W. Washington DC 20036. www.rferl.org