Anne Lo died of acute liver failure in January 2005.
A year earlier, she had been prescribed the drug, methotrexate, to treat her rheumatoid arthritis.
A police report tendered to the court says the dosage was increased two months before her death.
She complained of discomfort but was assured there was nothing wrong.
Mrs Lo then sought advice from another doctor and was diagnosed with hepatitis B and liver damage.
A forensic pathologist has told the court the drug can cause severe liver damage, especially if the patient has liver disease.
He said he could not work out what caused Mrs Lo's liver failure but it was possible there was a significant interaction between the hepatitis B infection and the medication. © 2007 Australian Broadcasting Corporation
