This advance has been the resulto f the research of the doctoral thesis "Growth hormone and osteointegration in the oral cavity" by Cecilia Vander Worf Úbeda, supervised by Professors Antonio Cutando Soriano and Gerardo Gómez Moreno (School of Odontology of the University of Granada, Spain).

"We must consider –says Cutando- that a dental impant is successful when it is possible to get a firm, stable and lasting joint between the bone substratum and the crown constructed on it, in which we call prosthetic restoration. That was the goal of this research work, which has also managed to improve the patients' quality of life reducing the wait period to receive a new tooth".

The Works were developed all through three years with a methodology applied to 13 dogs, with the authorization of the Ethical Committee of the University of Granada.

Hastened biointegration

The research carried out by Cecilia Vander Worf obtained a good and fast biointegration, which consists of "the direct biochemical joint between the raw bone and the surface of the implant, demonstrable through electronic microscopy, irrespective of any mechanical joint mechanism".

Osteointegration requires the formation of new bone around the implant, a process resulting from remodelling the interior of the bone tissue. "The process –says Vander Worf- starts with the osteoclasts, the cells responsible for reabsorbing the necrotic area originated by bone milling during the preparation of the bone recipient bed. Together with them, vascular neoformation will provide the cell elements, the osteoblasts, which will create new bone able to interact with the titanium oxide layer f the implant for the biological integration of it". -Universidad de Granada