Applied Data Research Analyzes Therapeutic, Economic and Compliance Factors Driving the Development of Targeted Drug Therapeutics
(Nashua, NH) – For many serious medical conditions, the success of available treatments is mitigated by unwanted side effects of the drug. Often these side effects can be debilitating and result in a dramatic impact on patient compliance. For decades, researchers and drug developers have searched for ways to minimize the severity and occurrence of this problem drug therapy. One of the most promising approaches is targeted drug delivery.
Drug targeting involves optimizing a drug’s therapeutic index by strictly localizing its pharmacological activity to the site or organ of action. Drug targeting can be achieved by physical, biological, or molecular systems that result in high concentrations of the pharmacologically active agent at the pathophysiologically relevant site. If successful, the result of the targeting would be a significant reduction in drug toxicity, reduction of the drug dose, and increased treatment efficacy.
Progress is accelerating into the design of delivery systems that can deliver an agent to the preferred site of action. Ongoing development includes the study of the macromolecular prodrug approach of linking a drug to a polymeric carrier. To increase the interaction of the drug with the target cells, target groups, such as peptides, are introduced to the polymer backbone. When such target groups or the drugs themselves are attached to the polymer backbone they can decrease the water solubility as well as the prodrug applicability, creating formulation challenges for developers.
A comprehensive report research and written by Applied Data Research documents and analyzes the results of a recent assessment of the evolving targeted drug delivery sector.
More information is also available at http://www.applieddata.org/Targeted_Drug_Delivery.htm
About Applied Data
Applied Data Research is a healthcare therapeutics consulting firm focused on medical market strategies, product commercialization, venture development, and market research. We assist medical market participants in achieving their business objectives through the creation of detailed business development strategies, product commercialization programs, and comprehensive market and technology research and analysis.
Contact:
Greg Stone
Voice: 603-595-6225
www.applieddata.org
Source: Applied Data Research
Comment and add to the story without registration, but keep the comments meaningful please. Links are not accepted.
