Aging

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Calorie Restriction May Benefit Only Obese Mice

If you are a mouse on the chubby side, then eating less may help you live longer, but calorie restriction does not help humans live longer shows the study.

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Researchers detail how aging undermines bone healing

Researchers have unraveled crucial details of how aging causes broken bones to heal slowly, or not at all, according to study results published today in the Journal of Bone and Mineral Research. The research team also successfully conducted preclinical tests on a potential new class of treatments designed to "rescue" healing capability lost to aging.

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Hormone therapy linked to brain shrinkage, but not lesions

Two new studies show that commonly prescribed forms of postmenopausal hormone therapy may slightly accelerate the loss of brain tissue in women 65 and older beyond what normally occurs with aging.

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Uncovering link between 2 aging pathways in mice

Two previously identified pathways associated with aging in mice are connected, say researchers at the Stanford University School of Medicine.

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Old gastrointestinal drug slows aging

Recent animal studies have shown that clioquinol – an 80-year old drug once used to treat diarrhea and other gastrointestinal disorders – can reverse the progression of Alzheimer's, Parkinson's and Huntington's diseases.

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Maintaining the brain's wiring in aging and disease

Researchers at the Babraham Institute near Cambridge, supported by the Alzheimer's Research Trust and the Biotechnology and Biological Sciences Research Council (BBSRC), have discovered that the brain's circuitry survives longer than previously thought in diseases of ageing such as Alzheimer's disease.

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Cellular senescence a double-edged sword

Scientists have identified a molecular cause behind the ravages of old age and in doing so have also shown how a natural process for fighting cancer in younger persons can actually promote cancer in older individuals.

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Preventing age-related brain changes in older adults

Older adults who exercise regularly show increased cerebral blood flow and a greater number of small blood vessels in the brain, according to findings presented today at the annual meeting of the Radiological Society of North America (RSNA).

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Antioxidants are unlikely to prevent aging

Diets and beauty products which claim to have anti-oxidant properties are unlikely to prevent ageing, according to research funded by the Wellcome Trust. Researchers at the Institute of Healthy Ageing at UCL (University College London) say this is because a key fifty year old theory about the causes of ageing is wrong.

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Researchers identify a potentially universal mechanism of aging

Like our current financial crisis, the aging process might also be a product excessive deregulation.

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Researchers Develop Drug To Cure Most Old Age Diseases

A new single class of drugs designed to cure old age diseases are all being developed in research labs. For so long diseases like cancer, diabetes, Parkinsons, Alzheimer’s and heart disease have resisted treatment. Now, researchers may have discovered the cure for diseases of old age.

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Sirtris' review of sirtuin therapeutics for diseases of aging

Sirtris, a GSK company focused on discovering and developing small molecule drugs to treat diseases of aging such as Type 2 Diabetes, announced today that it published a new review article on the growing body of sirtuin research and its potential to treat diseases of aging such as Type 2 Diabetes, mitochondrial disorders, inflammation, cancer, and heart disease.

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