University of Michigan scientists have provided the most detailed picture yet of a key HIV accessory protein that foils the body's normal immune response.

Key differences in immune system signaling and the production of specific immune regulatory molecules may explain why some primates are able to live with an immunodeficiency virus infection without progressing to AIDS-like illness, unlike other primate species, including rhesus macaques and humans, that succumb to disease.

The links between HIV transmission and the degree to which people are able to adopt realistic plans to achieve future projects, in other words, hope, have been overlooked in policies to tackle HIV/AIDS. New research funded by the Economic and Social Research Council (ESRC) argues that hope is a powerful tool in the battle to stop the spread of HIV/AIDS.

Johns Hopkins expert in HIV and how the AIDS virus hides in the body says antiretroviral drugs have stopped HIV from replicating, the first of three key steps needed to rid people of the virus.

Antiretroviral drugs for HIV do not increase the risk for coronary atherosclerosis, a central risk factor for heart disease, according to a study led by the University of Pittsburgh Graduate School of Public Health to be published in the Aug. 8 issue of the journal AIDS and available online today.

An evaluation of recent data has led to an update in the guidelines and recommendations for antiretroviral treatment of adult human immunodeficiency virus (HIV) infection, according to an article in the August 6 issue of JAMA, a theme issue on HIV/AIDS.

With the recent endorsement by the World Health Organization (WHO) and scientists worldwide of adult male circumcision as an important strategy for HIV prevention, there is increased urgency to develop safe and cost-effective circumcision services. This is especially the case in Africa where HIV/AIDS continues to spread at an epidemic rate.

One of the major reasons that treatment for HIV/AIDS often doesn't work as well as it should is resistance to the drugs involved. Now, scientists at McGill University have revealed how mutations hidden in previously ignored parts of the HIV genome play an important role in the development of drug resistance in AIDS patients.

A common vaginal infection may make women more susceptible to contracting HIV, the virus that causes AIDS, University of North Carolina at Chapel Hill School of Public Health researchers have found.

With tens of thousands due to gather in Mexico City Aug. 3 for the 2008 International AIDS Conference, the journal AIDS has published a special supplement that provides concrete recommendations for addressing the complex social and economic issues that fuel HIV.

Male injection drug users deported from the United States to Tijuana have four-fold higher odds of HIV infection compared to those living in Tijuana who were not deported there, according to a study to be presented at the International AIDS Conference on August 5, 2008 in Mexico City.

CD4+ T lymphocytes, or simply CD4 T cells, are the "brains" of the immune system, coordinating its activity when the body comes under attack. They are also the cells that are attacked by HIV, the devastating virus that causes AIDS and has infected roughly 40 million people worldwide. The virus slowly eats away at CD4 T cells, weakening the immune system.