Although children of alcoholics (COAs) have a greater risk of developing alcohol-use disorders (AUDs), not all COAs will develop AUDs. This study used functional magnetic resonance imaging (fMRI) to examine brain responses to emotional stimuli in adolescent COAs considered “vulnerable” or “resilient” to AUDs.
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Alcohol-use disorders have a significant genetic component to their development.
New findings show that heavy drinkers with the G allele of the A118G polymorphism of the mu-opioid receptor gene have greater cravings after alcohol exposure than heavy drinkers homozygous for the A allele.
Individuals with the G allele may have more problems resisting the urge to drink.
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