In what the researchers say could be promising news in the quest to find a therapy to slow the progression of amyotrophic lateral sclerosis (ALS), or Lou Gehrig’s disease, scientists at the University of California, San Diego (UCSD) School of Medicine have shown that targeting neuronal support cells called astrocytes sharply slows disease progression in mice.

A new Mayo Clinic study details an unprecedented method to predict brain aging disorders such as amyotrophic lateral sclerosis (ALS, or Lou Gehrig’s disease) and Parkinson’s disease.

Scientists have discovered a causal link between the gene for a small protein involved in the formation of blood vessels and the development of some forms of Motor Neurone Disease.

There is no known cure for amyotrophic lateral sclerosis (ALS), often known as Lou Gehrig disease and motor neuron disease. ALS is a progressive, fatal, neurodegenerative disease caused by the degeneration of nerves that control voluntary muscle movement.

University of Iowa researchers investigating the basic biology of cell signaling have made a discovery that may have therapeutic implications for amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases.

A University of California, Irvine neurologist is part of a national group of scientists who have identified the active genes in sporadic amyotrophic lateral sclerosis (ALS), a discovery that provides expanded opportunities for developing therapies to treat this chronic, incurable disease.

In a study that demonstrates the promise of cell-based therapies for diseases that have proved intractable to modern medicine, a team of scientists from the University of Wisconsin-Madison has shown it is possible to rescue the dying neurons characteristic of amyotrophic lateral sclerosis (ALS), a fatal neuromuscular disorder also known as Lou Gehrig's disease.

Chemists from UCLA and the University of Florence in Italy may have solved an important mystery about a protein that plays a key role in a particular form of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, a progressive, fatal neurodegenerative disorder that strikes without warning.

Moderate strengthening exercises may help people with early stage Amyotrophic lateral sclerosis maintain function and quality of life longer, according to a study published in the June 5, 2007, issue of Neurology®, the scientific journal of the American Academy of Neurology.

Researchers have discovered a new cellular mechanism that may better explain what causes amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's Disease.

Two papers by Columbia and Harvard researchers report for the first time that astrocytes (the most abundant non-neuronal cells in the central nervous system), which carry a mutated gene known to cause some cases of amyotrophic lateral sclerosis (ALS/Lou Gehrig's disease), induce motor neuron death. This indicates that astrocytes may contribute to ALS by releasing a toxic factor that damages neurons.