A recent study finds that the antidepressant effects of drugs like Prozac involve both neurogenesis-dependent and -independent mechanisms, a finding that may lead to development of better treatments for depression and anxiety.

New research into marketing by pharmaceutical companies has found that doctors and psychiatrists are being influenced by the branding of antidepressant drugs.

Researchers have identified subtle genetic variations that predict the efficacy of two widely used antidepressant drugs. They found that certain variants in the gene for a protective transporter protein that pumps drugs and other substances out of the brain compromise the effectiveness of the antidepressants citalopram (trade name Celexa) and venlafaxine (Effexor).

Boosting an exercise-related gene in the brain works as a powerful anti-depressant in mice—a finding that could lead to a new anti-depressant drug target, according to a Yale School of Medicine report in Nature Medicine.

NeuroMark, a Boulder, Colorado company, announced today the immediate availability of a genetic test to identify people at risk of suicidal ideation—thoughts of committing suicide—when prescribed an antidepressant drug.

There’s depression, and then there’s double depression.
Sound bad" It is, according to Thomas Joiner, Florida State University Distinguished Research Professor and the Bright-Burton Professor of Psychology, who has identified hopelessness as a distinguishing feature of double depression in a new paper published in the Journal of Affective Disorders.

Treatment of mice with a 'friendly' bacteria, normally found in the soil, altered their behavior in a way similar to that produced by antidepressant drugs, reports research published in the latest issue of Neuroscience.