Fulminant hepatic failure is a serious clinical disease and may threaten the life of patients. However, because of the damage of mass liver cells, the organ function is often irreversible due to the liver cell degeneration, swelling, or apoptosis.

Apoptosis is a programmed, active, highly selective mechanism of cell death. Abnormal regulation of apoptosis can lead to disorders such as cancer. The field of apoptosis research has undergone an explosion of new knowledge over the past decade.

Isoforms from Novel Structure Proteins (NSP), a new family of genes discovered by researchers in the Sbarro Institute for Cancer Research and Molecular Medicine in Temple University's College of Science and Technology, could be involved in apoptosis or programmed cell death.

Under 10 mmHg CO2 pressure, there were no obvious effects on MKN-45 cellsЎЇ proliferation and apoptosis. At 15 mmHg CO2 insufflation pressure, cells proliferation was inhibited and apoptosis improved. It may be that CO2 gas affected the growth of gastric cancer cells.

Investigators at St. Jude Children’s Research Hospital have discovered a dance of proteins that protects certain cells from undergoing apoptosis, also known as programmed cell death. Understanding the fine points of apoptosis is important to researchers seeking ways to control this process.

Sometimes healthy cells commit suicide. In the 1970s, scientists showed that a type of programmed cell death called apoptosis plays a key role in development, and the 2002 Nobel Prize in Physiology or Medicine recognized their work. As apoptotic cells degrade, they display standard characteristics, including irregular bulges in the membrane and nuclear fragmentation.

Changes in the size, shape, and function of the heart (cardiac remodeling) contribute to the onset and progression of heart failure.

Scientists at the University of California, Santa Barbara have made a significant discovery relating to viral infections in humans.

An overexpressed protein protects human pancreatic cancer cells from being forced to devour themselves, removing one of the body's natural defenses against out-of-control cell growth, researchers at The University of Texas M. D. Anderson Cancer Center report in the March issue of Molecular Cancer Research.