autoimmune disease

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Pesearchers probe kidney damage, protection in lupus

Kidney damage associated with the autoimmune disease lupus is linked to a malfunction of immune cells that causes them to congregate in and attack the organs, researchers at UT Southwestern Medical Center have discovered in a mouse study.

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Vitamin D may exacerbate autoimmune disease

Deficiency in vitamin D has been widely regarded as contributing to autoimmune disease, but a review appearing in Autoimmunity Reviews explains that low levels of vitamin D in patients with autoimmune disease may be a result rather than a cause of disease and that supplementing with vitamin D may actually exacerbate autoimmune disease.

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Fireflies and jellyfish help illuminate quest for cause of infertility

Genes taken from fireflies and jellyfish are literally shedding light on possible causes of infertility and autoimmune diseases in humans.

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New structural motif in key enzymes is essential to prevent autoimmune disease

Scientists from the Scripps Research Institute and the Genomics Institute of the Novartis Research Foundation have found a specific mutation that leads to the development of severe autoimmune kidney disease in mice.

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Neurotransmitter defect may trigger autoimmune disease

A potentially blinding neurological disorder, often confused with multiple sclerosis (MS), has now become a little less mysterious. A new study by researchers at the Mayo Clinic in Rochester, Minnesota, may have uncovered the cause of Devic's disease.

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Type 1 diabetes may result from good genes behaving badly

New research from Stanford University scientists suggests that type 1 diabetes, an autoimmune disease that develops in children and young adults, may not be due to bad genes but rather to good genes behaving badly.

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Despite Risks, Powerful Drugs Offer Hope and Relief to Autoimmune Patients

New Survey by Applied Data Research Analyzes Therapeutic and Commercial Factors in Treating Autoimmune Diseases

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Lung inflammation from influenza could be turned off with new discovery

A new discovery could lead to treatments which turn off the inflammation in the lungs caused by influenza and other infections, according to a study published today in the journal Nature Immunology.

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Pre-eclampsia may be autoimmune disease

Biochemists at The University of Texas Medical School at Houston say they are the first to provide pre-clinical evidence that pregnancy-induced high blood pressure or pre-eclampsia may be an autoimmune disease. Their research could provide novel diagnostic and therapeutic possibilities for this intractable disease. Findings appear online in Nature Medicine on July 27.

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Dartmouth researchers discover gene signatures for scleroderma

Distinct genetic profiles can discern different groups of patients with scleroderma, a vexing autoimmune disease in which the body turns against itself, Dartmouth Medical School researchers report.

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Strengthening the tumor-fighting ability of T cells

When faced with cancer, the immune system dispatches cells, called T cells, to kill the tumor. But these killer cells often fail to completely eliminate the tumor because they’re deactivated by a distinct population of T cells known as regulatory T cells.

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Significance and limitations of new lupus gene expression research

Some 1.5 million Americans, most of them women, suffer from lupus, a disease where the person’s immune system attacks the body’s own tissue. This week marks a significant step forward in understanding how the disease works with the online publication of four new studies identifying genes involved in this often debilitating chronic disease.

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