biomarkers

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Biomarker discovery for better cancer diagnostics

While new findings from Ohio State University scientists suggest a genetic marker that could help distinguish between chronic pancreatitis and pancreatic cancer and gauge who will do well with cancer treatment, a pharmacologist at the Kimmel Cancer Center at Jefferson in Philadelphia sees the discovery as much more.

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Biomarkers warn of impending injury from repetitive motion

For the first time in humans, scientists have found early indicators of inflammation - potential warning signs - in work-related injuries caused by repetitive motion.

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Severe form of 'enlarged prostate' disease discovered

Millions of middle-aged and older men experience the symptoms of an enlarged prostate multiple times during the day and night. What they may not know is that the disease known as BPH (benign prostatic hyperplasia), marked by urgency and frequent urination, is not one but at least a pair of disorders, and that one of the pair Ї tied to a newly identified gene Ї has far more serious implications.

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Selective marker to indicate aggressive form of breast cancer

Researchers have linked a structural protein called nestin to a particularly deadly form of breast cancer, identifying a new biomarker that could lead to earlier detection and better treatment.

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Role for proteomics in identifying hematologic malignancies

Scientists have identified a set of biomarkers that could help clinicians identify a group of hematologic malignancies known as myelodysplastic syndromes (MDS), which affect approximately 300,000 individuals worldwide and often progress to acute myeloid leukemia.

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Two biomarkers with potential to predict breast cancer spread

Expression of two different proteins taken from primary tumor biopsies is highly associated with spread of breast cancer to nearby lymph nodes, according to researchers who say this protein profile could help identify at an early stage those patients whose disease is likely to metastasize.

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