An important discovery has been made with respect to the mystery of “handedness” in biomolecules. Researchers led by Sandra Pizzarello, a research professor at Arizona State University, found that some of the possible abiotic precursors to the origin of life on Earth have been shown to carry “handedness” in a larger number than previously thought.
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Scientists at Carnegie Mellon University's Molecular Biosensor and Imaging Center (MBIC) have developed new "fluorogen activating proteins" (FAPs) that will become a key component of novel molecular biosensor technology being created at Carnegie Mellon. The FAPs, which can be used to monitor biological activities of individual proteins and other biomolecules within living cells in real time, are described in the February issue of Nature Biotechnology.
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A research team at Penn State has developed a novel method for attaching small molecules, such as neurotransmitters, to surfaces, which then are used to capture large biomolecules.
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Click chemistry, one of the most exciting and proficient new techniques for labeling biomolecules in vitro, has now been extended to studies in the context of live cells as well. This breakthrough opens the door for applications to live cell imaging of numerous biomolecules, including glycans, proteins and lipids. The new version of click chemistry was developed by researchers with the Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California (UC) at Berkeley.
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Click chemistry, one of the most exciting and proficient new techniques for labeling biomolecules in vitro, has now been extended to studies in the context of live cells as well. This breakthrough opens the door for applications to live cell imaging of numerous biomolecules, including glycans, proteins and lipids. The new version of click chemistry was developed by researchers with the Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California (UC) at Berkeley.
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Magnetic switches like those in computers also might be used to manipulate individual strands of DNA for high-speed applications such as gene sequencing, experiments at the National Institute of Standards and Technology (NIST) suggest.
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Biochip platforms that work as artificial cells are attractive for medical diagnostics, interrogation of biological processes, and for the production of important biomolecules. However, to match the complexity of nature, the biochips need to be designed such that proteins, DNA, and other important biological components can be located in specific, spatially well-defined regions on the chips.
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