Brain cells

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Breakdown in system which regulates appetite and weight

New research led by scientists at the Oregon National Primate Research Center demonstrates how obesity causes the breakdown of a brain system that regulates appetite. The research provides a clear picture of some factors involved in obesity.

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Genetic risk factors for Alzheimer's disease

Cardiff University researchers have found evidence for new genes involved in the development of Alzheimer's disease.

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Genetic fingerprints identify brain tumors' origins

Genetic fingerprints that reveal where a brain cell came from remain distinct even after the cell becomes a brain tumor, an international coalition of scientists will report in the February 1 issue of Cancer Research

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McMaster researchers discover zip codes for protein

McMaster scientists are very close to defining small molecule drugs that should be able to redirect the huntingtin protein from accumulating in the wrong place within brain cells, which could potentially translate to a therapy for Huntington's Disease (HD).

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Major link in brain-obesity puzzle found

A single protein in brain cells may act as a linchpin in the body's weight-regulating system, playing a key role in the flurry of signals that govern fat storage, sugar use, energy balance and weight, University of Michigan Medical School researchers report.

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New method for treating brain injuries

An injury to the brain can be devastating. When brain cells die, whether from head trauma, stroke or disease, a substance called glutamate floods the surrounding areas, overloading the cells in its path and setting off a chain reaction that damages whole swathes of tissue.

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How appetite-stimulating brain cells work overtime during fasting

During periods of fasting, brain cells responsible for stimulating the appetite make sure that you stay hungry. Now, a new study of mice reported in the January issue of the journal Cell Metabolism, published by Cell Press, reveals the complex series of molecular events that keep those neurons active.

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MIT creates 3-D scaffold for growing stem cells

Stem cells grew, multiplied and differentiated into brain cells on a new three-dimensional scaffold of tiny protein fragments designed to be more like a living body than any other cell culture system.

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Neurons targeted by dementing illness may have evolved for complex social cognition

Von Economo neurons (VENs) are uniquely shaped brain cells that seem to have evolved in a select group of socially complex species: great apes, humans, and, as reported last month, whales. Across species, VENs are localized to frontal brain regions associated with cognition, emotion and social behavior.

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Cellular cues identified for stroke recovery

New insight into how the brain regenerates after stroke

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