brain disease

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Genetic mutation causes familial susceptibility for degenerative brain disease

Mutation of a gene that helps proteins migrate in and out of the cell's genetic command center – the nucleus – puts some families at higher risk for the degenerative brain disease acute necrotizing encephalopathy (ANE).

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Impaired energy metabolism linked with initiation of plaques in Alzheimer's brain

Scientists have identified an initiating molecular mechanism in sporadic Alzheimer's disease (AD). The study, published by Cell Press in the December 26th issue of the journal Neuron, provides new information about generation of damaging amyloid β (Aβ) plaques within the AD brain and underscores the importance of developing new preventative and disease-modifying therapies for AD, especially those aimed at interrupting pathological Aβ-production.

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Brain starvation as we age appears to trigger Alzheimer's

A slow, chronic starvation of the brain as we age appears to be one of the major triggers of a biochemical process that causes some forms of Alzheimer's disease.

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Study sheds light on causes of HIV dementia

Findings on how major HIV strains affect the brain differently could lead to better treatments

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Multiple sclerosis progression can be predicted with MRI

A new study published in Journal of Neuroimaging shows that MRI scans used on multiple sclerosis (MS) patients to determine if the disease has affected gray matter in the brain can identify those at-risk for progression of disability.

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Antimicrobial sutures reduce infections in brain shunt surgery

Children born with hydrocephalus, or "water on the brain" must have shunts implanted to drain the fluid away from the brain to reduce harmful pressure.

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Loss of stability of the AHI1-HAP1 complex an issue in Joubert syndrome

Joubert syndrome is an inherited disorder that affects the area of the brain that controls balance and coordination; it is characterized by symptoms such as loss of muscle tone, developmental delay, and mental retardation.

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Means of reducing Alzheimer's-like plaques in fly brain

Neuroscientists at Cold Spring Harbor Laboratory (CSHL) are part of a collaboration that has succeeded in demonstrating that overexpression of an enzyme in the brain can reduce telltale deposits causally linked with Alzheimer's disease.

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Japanese encephalitis virus causes double trouble to brain

Japanese encephalitis (JE), commonly known as brain fever, is one of the prevalent mosquito-borne encephalitis in India and entire South East (SE) Asia.

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Discovery will assist treatment and research into fatal brain disorder

Research using newly developed Magnetic Resonance Imaging technology could soon allow clinicians to confirm Huntington's disease before symptoms appear in people who have the gene for the fatal brain disease.

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Developing unique brain maps to assist surgery and research

Researchers from the Howard Florey Institute in Melbourne are developing new technology to create individualised brain maps that will revolutionise diagnosis of disease and enhance the accuracy of brain surgery.

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Long-term cannabis users may have structural brain abnormalities

Long-term, heavy cannabis use may be associated with structural abnormalities in areas of the brain known as the hippocampus and amygdala, according to a report in the June issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

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