An extended analysis of cancer rates reinforces a strong association between use of hormone replacement therapy (HRT) and increased breast cancer incidence, according to research led by scientists at The University of Texas M. D. Anderson Cancer Center and published in the April 19th issue of the New England Journal of Medicine.
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A new high-throughput genetic analysis technique can reveal gene markers - by the dozens - that determine how a patient might respond to certain cancer drugs, according to scientists at the Translational Genomics Research Institute (TGen).
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Researchers at Lawrence Berkeley National Laboratory have identified gene expression signatures that could serve as biomarkers to predict how individuals will respond to the breast cancer drugs lapatinib and CI-1040. Their findings could help in individualizing treatments for women, and their methodologies could aid in identifying similar biomarkers for responses to other drugs and for other types of cancer.
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By combining two techniques, magnetic resonance imaging (MRI) and near-infrared optics, researchers at Dartmouth College and Dartmouth Medical School may have devised a new, potentially more accurate method for diagnosing breast cancer. Their pilot study, demonstrating the feasibility of the concept, is published in the April 15 issue of the journal Optics Letters, published by the Optical Society of America.
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Researchers at the Kimmel Cancer Center at Jefferson have identified a protein that they say is key to helping a quarter of all breast cancers spread. The finding, reported online the week of April 9, 2007 in the journal Proceedings of the National Academy of Sciences, could be a potential target for new drugs aimed at stopping or slowing the growth and progression of breast cancer.
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FDA approves Tykerb (lapatinib) in combination with Xeloda (capecitabine) for the treatment of advanced or metastatic breast cancer in women who have progressed on prior therapy. GlaxoSmithKline's New Breast Cancer Drug May Give Women More Options
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In an ideal world, the answer is no, as breast milk transmission of HIV contributes substantially to infant infection. However, in the same developing countries where the majority of HIV mother-to-child transmission takes place, breast milk is often considered the only safe and nutritious food for infants.
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The active ingredient in a drug currently being tested to treat rheumatoid arthritis might also one day serve as an effective means of treating one of the deadliest forms of breast cancer. Researchers with the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) have demonstrated that inhibiting the activity of the protease enzyme known as TACE can deprive tumor cells of a key factor needed for their proliferation.
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Giving radiation therapy and chemotherapy at the same time after a lumpectomy helps keep breast cancer from returning locally, according to a study published in the December 1 issue of the International Journal of Radiation Oncology*Biology*Physics, the official journal of ASTRO.
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