C. diff-associated disease (CDAD), otherwise known as severe intestinal disease brought on by the Clostridium difficile (C. diff) pathogen, has been the subject of heightened concern in the medical community. A new report released this month by the federal Agency for Healthcare Research and Quality revealed a 200 percent increase in potentially fatal diarrheal infections in U.S. hospitals between 2000 and 2005.

The Association for Professionals in Infection Control and Epidemiology (APIC) today announced a detailed strategy to combat Clostridium difficile-associated disease (CDAD). The initiative begins with the first national prevalence study to gain a better understanding of the spread of this virulent pathogen.

The bacterium that causes a highly contagious and sometimes deadly form of diarrhea is frequently carried by persons who do not have any of the disease symptoms, according to a study in the Oct. 15 issue of Clinical Infectious Diseases, now available online.

Hospitals world-wide battle nosocomial infections on a daily basis. One of the most difficult bacteria to combat is Clostridium.difficile. To help ensure the best control methods possible, Dr. Michael Libman, Director of the Division of Infectious Diseases at the McGill University Health Centre (MUHC), studied the most effective ways to eliminate C.difficile bacteria from the hands of health care workers, with the highest honour going to soap and warm water!

Researchers studying the genetics behind why C. difficile causes disease have come to a simple conclusion -- the bacteria do it because they are starving. That just might help them find a new treatment for what can sometimes be a very difficult disease to treat.