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New Way to Study How Breast Cancer Spreads

In a breakthrough study appearing in advance online publication of Nature Methods, researchers at Albert Einstein College of Medicine of Yeshiva University describe for the first time a method of viewing individual breast cancer cells for several days at a time. The study, by scientists in Einstein's Gruss Lipper Biophotonics Center, provides detail on how cancer cells invade surrounding tissue and reach blood vessels.

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Starving cancer cells of arginine cuts proliferation in half

UC Davis Cancer Center researchers have discovered a metabolic deficiency in pancreatic cancer cells that can be used to slow the progress of the deadliest of all cancers.

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New way of inhibiting cell cycle shows promise

A new anti-cancer compound that works by blocking a part of the cell's machinery that is crucial for cell division has shown promising results in a phase I clinical trial in patients who have failed to respond to other treatments.

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Scientists unlock secret of death protein's activation

Scientists at Dana-Farber Cancer Institute have identified a previously undetected trigger point on a naturally occurring "death protein" that helps the body get rid of unwanted or diseased cells. They say it may be possible to exploit the newly found trigger as a target for designer drugs that would treat cancer by forcing malignant cells to commit suicide.

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New cancer-killing compound from salad plant

Researchers at the University of Washington have updated a traditional Chinese medicine to create a compound that is more than 1,200 times more specific in killing certain kinds of cancer cells than currently available drugs, heralding the possibility of a more effective chemotherapy drug with minimal side effects.

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Burnham researchers turn cancer friend into cancer foe

Burnham Institute for Medical Research today announced that scientists have created a peptide that binds to Bcl-2, a protein that protects cancer cells from programmed cell death, and converts it into a cancer cell killer. The research, which was published as the featured article in the October 7 edition of Cancer Cell, may lead to new cancer treatments.

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Scientists trace novel way cells are disrupted in cancer

A research team at Cold Spring Harbor Laboratory (CSHL) is clarifying a previously unappreciated way that cellular processes are disrupted in cancer.

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Mechanism to promote metastasis in human cancer cells

Virginia Commonwealth University Institute of Molecular Medicine and VCU Massey Cancer Center researchers have discovered how a gene, melanoma differentiation associated gene-9/syntenin (mda-9/syntenin), interacts with an important signaling protein to promote metastasis in human melanoma cells, a discovery that could one day lead to the development of the next generation of anti-metastatic drugs for melanoma and other cancers.

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Toxic genes to effectively kill pancreatic cancer cells

A research team, led by investigators at the Department of Surgery at Jefferson Medical College of Thomas Jefferson University and the Kimmel Cancer Center at Jefferson, has achieved a substantial "kill" of pancreatic cancer cells by using nanoparticles to successfully deliver a deadly diphtheria toxin gene.

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How to make cancer vulnerable to good viruses

Researchers at McGill University and the affiliated Lady Davis Research Institute of the Jewish General Hospital – along with colleagues at the University of Ottawa and the Ottawa Health Research Institute (OHRI) –report a significant breakthrough in the use of viruses to target and destroy cancer cells, a field known as oncolytic virotherapy.

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Putting microRNAs on the stem cell map

Embryonic stem cells are always facing a choice—either to self-renew or begin morphing into another type of cell altogether.

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Researchers find cancer-inhibiting compound under sea

University of Florida College of Pharmacy researchers have discovered a marine compound off the coast of Key Largo that inhibits cancer cell growth in laboratory tests, a finding they hope will fuel the development of new drugs to better battle the disease.

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