The protein IKKalpha (IKKα) regulates the cell cycle of keratinocytes and plays a key role in keeping these specialized skin cells from becoming malignant, researchers at The University of Texas M. D. Anderson Cancer Center report in the Sept. 9 issue of Cancer Cell.

Chronic inflammation of the intestine or stomach can damage DNA, increasing the risk of cancer, MIT scientists have confirmed.

According to a new study, patients are receiving estimated doses of radiation from medical diagnostic imaging studies, such as CT (or “CAT”) scans, that may be detrimental to their long term health, putting them at an increased risk of developing cancer. To date, emergency physicians have not been made aware of the cumulative amount of radiation that their patients receive.

Combining natural organic atoms with metal complexes, scientists at The Wistar Institute have developed a new type of enzyme inhibitor capable of blocking a biochemical pathway that plays a key role in cancer development.

Oregon Health & Science University researchers have identified a gene that is necessary in eliminating cancer cells.

Scientists have established a mouse model for human malignant mesothelioma (MM) that will provide valuable insight into cancer development and progression along with new directions for design of therapeutic strategies.

Researchers have identified a potential new mechanism through which human T-lymphotropic virus type-1 (HTLV-1) causes leukemia in adults. The findings, published this week in the online open access journal Retrovirology, represent the first time that a reduction in histone protein levels has been linked to viral infection and the development of cancer.

They say that a picture can be worth a thousand words. This especially is true for describing the structures of molecules that function to promote cancer.

Researchers at Johns Hopkins have discovered that cancers arising from epigenetic changes - in this case the inappropriate activation of a normally silent gene - develop by becoming addicted to certain growth factors.

The study shows that overweight and obese women in the UK are at a higher risk of developing and dying from cancer. In fact, the researchers estimate that 5% of all cancers (about 6,000 annually) are attributable to being overweight or obese.

Scientists at Johns Hopkins recently discovered that a chemical chain reaction that controls organ size in animals ranging from insects to humans could mean the difference between normal growth and cancer.

Working the night shift doesn't appear to increase the risk of developing cancer, suggests the findings of a new study of Swedish workers.