Cancer Treatment

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Newly Found Enzymes May Play Early Role in Cancer

Researchers have discovered two enzymes that, when combined, could be involved in the earliest stages of cancer. Manipulating these enzymes genetically might lead to targeted treatments aimed at slowing or preventing the onset of tumors.

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Scientists show how certain vegetables combat cancer

Women should go for the broccoli when the relish tray comes around during holiday celebrations this season.

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Key Step in Maturation Pathway of Telomerase

The Stowers Institute’s Baumann Lab has discovered an important step in the maturation pathway of telomerase, the enzyme that replenishes the sequences that are lost at chromosome ends with every cell division. The findings were published today in the Advance Online Publication of Nature.

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Cellular senescence a double-edged sword

Scientists have identified a molecular cause behind the ravages of old age and in doing so have also shown how a natural process for fighting cancer in younger persons can actually promote cancer in older individuals.

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Broccoli compound targets key enzyme in late-stage cancer

An anti-cancer compound found in broccoli and cabbage works by lowering the activity of an enzyme associated with rapidly advancing breast cancer, according to a University of California, Berkeley, study appearing this week in the online early edition of the journal Proceedings of the National Academy of Sciences.

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Researchers discover critical process in cancer treatment

From the sun's UVA rays to tobacco smoke, our environment is chock-full of DNA-damaging agents that can lead to cancer. Thanks to our body's DNA repair mechanisms, however, the effects of many carcinogens can be reversed thereby preventing the formation of tumours.

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Researcher sequence genome of cancer patient

For the first time, scientists have decoded the complete DNA of a cancer patient and traced her disease - acute myelogenous leukemia - to its genetic roots. A large research team at the Genome Sequencing Center and the Siteman Cancer Center at Washington University School of Medicine in St. Louis sequenced the genome of the patient - a woman in her 50s who ultimately died of her disease - and the genome of her leukemia cells, to identify genetic changes unique to her cancer.

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High throughput imaging speeds analysis of hormone receptors

A new high throughput microscopy technique enabled researchers at Baylor College of Medicine in Houston to analyze thousands of individual cells expressing androgen receptor, a finding that could herald new ways of evaluating the effect of drugs or other treatments on cells with normal or aberrant hormone receptors.

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The richness of antioxidants against tumors

High anthocyanins content tomatoes, produced by European researchers, may be able to extend lifespan in cancer-prone mice; the finding by the FLORA European Project published in the journal Nature Biotechnology

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Link between gene variations and cancer survival

Scientific research shows that certain genes can influence a person's likelihood to contract particular diseases, cancer for example. New research at the Masonic Cancer Center, University of Minnesota demonstrates that genetic markers may also show a person's likelihood to survive the disease.

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Healthy eating can improve cancer patients' response to chemotherapy

The leading cause of death in all cancer patients continues to be the resistance of tumor cells to chemotherapy, a form of treatment in which chemicals are used to kill cells.

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Assessing the quality of phase I clinical trial abstracts

Researchers have developed a method of assessing the quality of phase I clinical trial abstracts submitted to two different oncology conferences: EORTC-NCI-AACR (ENA) and American Society of Clinical Oncology (ASCO).

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