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Racial and Geographic Disparities in Surgical Therapy for Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC), a cancer of cells in the liver, is on the rise in part due to the high prevalence of chronic hepatitis C infection, which increases the risk for the disease. Surgery is the only potential curative treatment for HCC and this study sought to determine the patterns of use for this treatment.

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Vegetarian diet reduces risk of Colorectal Cancer

The average person's lifetime risk of developing colorectal cancer (CRC) is about seven percent and the role of diet in preventing this type of cancer remains under debate. Most of all, previous studies enrolled middle-aged subjects, raising the possibility that CRC development may start before common interventions. Researchers from Tata Memorial Hospital (TMH) in Mumbai, India, set out to determine whether a vegetarian diet is associated with reduced risk of CRC if started very early in life.

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Decoding gene expression in cancer tumors

By correlating images of cancerous liver tissue with gene expression patterns, a research team led by a radiologist at the University of California, San Diego (UCSD) School of Medicine has developed tools that may some day allow physicians to view a CT image of a cancer tumor and discern its genetic activity.

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Some vitamin supplements don't protect against lung cancer

A study of more than 75,000 adults found that taking supplemental multivitamins, vitamin C and E and folate do not decrease the risk of lung cancer. The findings are being reported at the American Thoracic Society 2007 International Conference, on Monday, May 21.

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Genetic marker linked to aggressive prostate cancer

Northwestern University researchers have discovered that a recently identified genetic marker for prostate cancer is linked to a highly aggressive form of the disease.

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Nanocomposite labeled cancer cells can be destroyed using lasers

A nanocomposite particle can be constructed so that it has a mix of properties that would not otherwise happen in nature. By combining an organic matrix with metallic clusters that can absorb light, it is possible to incorporate such particles into cells and then destroy those targeted cells with a laser.

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Nanoparticles incorporating siRNA promise to treate cancer

The use of targeted nanoparticles offers promising techniques for cancer treatment. Researchers in the laboratory of Mark E. Davis at the California Institute of Technology have been using small interfering RNA (siRNA), sometimes known as silencing RNA, to "silence" specific genes that are implicated in certain malignancies.

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Veterans exposed to Agent Orange have higher rates of prostate cancer recurrence

Veterans exposed to Agent Orange have a 48 percent increased risk of prostate cancer recurrence following surgery than their unexposed peers, and when the disease comes back, it seems more aggressive, researchers say.

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Role of TRPM8 in the development of prostate cancer

Recent studies have indicated that the protein known as TRPM8 plays an important role in prostate cancer: high levels of TRPM8 have been found in prostate carcinoma compared to normal prostate epithelial cells, and TRPM8 has been suggested as a specific marker and therapeutic target in prostate cancer. However, the regulation of and changes in TRPM8 during prostate cancer progression have remained unclear.

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Combining NSAIDs with chemotherapy to improve cancer treatment

Until recently, nonsteroidal anti-inflammatory drugs (NSAIDs) like aspirin and celecoxib (sold as Celebrex), were being hailed as promising cancer prevention drugs. However, the latest studies have concluded that in most cases the adverse side effect of these drugs - including risk of cardiovascular and kidney disease - outweigh the potential benefit.

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Beliefs about cancer cause to ignore cancer prevention advice

If you feel that you are fated for cancer, your belief could turn into a self-fulfilling prophecy. According to a national survey of more than 6,000 U.S. adults published in the May issue of Cancer Epidemiology, Biomarkers & Prevention, a substantial number of American adults hold fatalistic beliefs about cancer and are correspondingly less likely to take basic steps to lower their cancer risk, such as exercising, quitting smoking and eating a healthy diet rich in fruits and vegetables.

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Tomatoes against prostate cancer

Tomatoes might be nutritious and tasty, but don't count on them to prevent prostate cancer. In the May issue of Cancer Epidemiology, Biomarkers & Prevention, researchers based at the National Cancer Institute and Fred Hutchinson Cancer Research Center report that lycopene, an antioxidant predominately found in tomatoes, does not effectively prevent prostate cancer.

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