New scientific evidence is helping to build a compelling case for oncolytic viruses as a first-line and adjunctive treatment for many cancers.

A fundamental genetic mechanism that shuts down an important gene in healthy immune system cells has been discovered that could one day lead to new therapies against infections, leukemia and other cancers. Results of a University of Pittsburgh School of Medicine study on the mechanism, called a somatic stop-codon mutation, are being reported today in the online journal PLoS ONE, published by the Public Library of Science.

An earlier indication of whether chemotherapy benefits non-small cell lung cancer patients-provided by positron emission tomography (PET) imaging-can guide doctors in offering them better care, according to researchers in the May Journal of Nuclear Medicine.

Higher Colon Cancer Risk in Uveal Melanoma Patients and Their Relatives Compared to General Population, will be presented by Frederick H. Davidorf, MD, during the Association for Research in Vision and Ophthalmology (ARVO) 2007 Annual Meeting in Fort Lauderdale, Fla. The presentation will take place on Wednesday, May 9 from 3:00 p.m. to 4:45 p.m. in Hall B/C of the Greater Fort Lauderdale/Broward County Convention Center.

A combination of molecular-targeted therapy and hormonal therapy may be the most promising area of research for those seeking an effective treatment for ovarian cancer, according to a new review in the International Journal of Gynecological Cancer.

A drug that targets the body's immune cells may be effective in treating malignant brain tumors, according to a new study led by researchers at Duke's Preston Robert Tisch Brain Tumor Center. In animal models, the drug re-engaged the body's cancer-damaged immune system.

Scientists with the Lineberger Comprehensive Cancer Center at the University of North Carolina at Chapel Hill have for the first time implicated a growth-promoting cellular protein as one trigger of the inevitable recurrence of advanced prostate cancer in men who are undergoing drug treatment to shut down their sex hormones, or androgens.

One simple blood test could predict relapse or survival for children and young adults with acute leukemias, researchers from the Children's Cancer Hospital at The University of Texas M. D. Anderson Cancer Center reported at the American Society of Pediatric Hematology Oncology's annual meeting Saturday, May 5.

Exposure to particles of depleted uranium (DU), the source of growing international concern as a potential health hazard, may increase the risk of genetic damage and lung cancer, scientists in Maine conclude in a report scheduled for the May 21 issue of ACS' Chemical Research in Toxicology, a monthly journal.

In a study that could point to novel therapies to prevent cancer spread, or metastasis, researchers at the University of California, San Diego (UCSD) School of Medicine have targeted a sugar that supports blood vessel growth in the tumor. Their findings will be published in the May 7 on-line issue of Journal of Cell Biology.

Ultrasound-guided cryoablation of small breast cancer may be a safe procedure associated with minimal morbidity and high patient satisfaction, according to a recent case report by radiologists at the University of Wisconsin Hospital & Clinics in Madison, WI.

The use of computer-aided detection (CAD) with computed radiography (CR) is effective in the detection of breast cancer, according to a recent study conducted by radiologists at George Washington University Medical Center in Washington, DC and iCAD in Nashua, NH.