By using ultrafast laser pulses to slice off pieces of chromosomes and observe how the chromosomes behave, biomedical engineers at the University of Michigan have gained pivotal insights into mitosis, the process of cell division.
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Researchers have long known that some repetitive DNA sequences can make human chromosomes "fragile," i.e. appearing constricted or even broken during cell divisions.
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A group of Dartmouth researchers has found a new function for one of the proteins involved with chromosome segregation during cell division. Their finding adds to the growing knowledge about the fundamental workings of cells, and contributes to understanding how cell function can go wrong, as it does with cancerous cells.
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The Stowers Institute’s Baumann Lab has discovered an important step in the maturation pathway of telomerase, the enzyme that replenishes the sequences that are lost at chromosome ends with every cell division. The findings were published today in the Advance Online Publication of Nature.
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Biologists have discovered a mechanism that is critical to cytokinesis -- nature's completion of mitosis, where a cell divides into two identical daughter cells.
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A Swedish research group, partly financed by NWO, has discovered a new mechanism for cell division in a microorganism found in extremely hot and acidic conditions. The results of the research offer insights into evolution, but also into the functioning of the human body. The research has been recently published in PNAS, the magazine of the American National Academy of Sciences.
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A Florida State University College of Medicine research team led by Yanchang Wang has discovered an important new layer of regulation in the cell division cycle, which could lead to a greater understanding of the way cancer begins.
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A novel cell division mechanism has been discovered in a microorganism that thrives in hot acid. The finding may also result in insights into key processes in human cells, and in a better understanding of the main evolutionary lineages of life on Earth.
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The Stowers Institute's Rong Li Lab has characterized a mechanism that allows for asymmetrical cell division during meiosis in oocytes. By tracking chromosome movement in live mouse oocytes, the team discovered that chromosomes can recruit to their vicinity a protein called formin-2.
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Micromanagers may generate resentment in an office setting, but they get results in your body. New data indicate that a dividing cell takes micromanagement to the extreme, tagging more than 14,000 different sites on its proteins with phosphate, a molecule that typically serves as a signal for a variety of biological processes.
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Every cell contains a tiny clock called a telomere, which shortens each time the cell divides. Short telomeres are linked to a range of human diseases, including HIV, osteoporosis, heart disease and aging.
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Viruses are masters of deception, duping their host's cells into helping them grow and spread. A new study has found that human cytomegalovirus (HCMV) can mimic a common regulatory protein to hijack normal cell growth machinery, disrupting a cell's primary anti-cancer mechanism.
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