With improved resolution, tissue-specific molecular markers and precise timing, University of Oregon biologist James A. Weston and colleagues have possibly overturned a long-standing assumption about the origin of embryonic cells that give rise to connective and skeletal tissues that form the base of the skull and facial structures in back-boned creatures from fish to humans.
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Replacing one amino acid on the surface of a virus that shepherds corrective genes into cells could be the breakthrough scientists have needed to make gene therapy a more viable option for treating genetic diseases such as hemophilia, University of Florida researchers say.
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A team of Penn State researchers has developed a simple artificial cell with which to investigate the organization and function of two of the most basic cell components: the cell membrane and the cytoplasm--the gelatinous fluid that surrounds the structures in living cells.
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Now that the genome (DNA) of humans and many other organisms have been sequenced, biologists are turning their attention to discovering how the many thousands of structural and control genes -- the “worker bees” of living cells that can turn genes on and off -- function.
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Real or perceived threats can trigger the well-known “fight or flight response” in humans and other animals. Adrenaline flows, and the stressed individual’s heart pumps faster, the muscles work harder, the brain sharpens and non-essential systems shut down. The whole organism responds in concert in order to survive.
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A small, unmanned vehicle makes its way down the road ahead of a military convoy. Suddenly it stops and relays a warning to the convoy commander. The presence of a deadly improvised explosive device, or IED, has been detected by sophisticated new sensor technology incorporating living olfactory cells on microchips mounted on the unmanned vehicle. The IED is safely dismantled and lives are saved.
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Until recently, the chemical marks littering the DNA inside our cells like trees dotting a landscape could only be studied one gene at a time.
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Looking for answers in the bright light of day, rather than the confined beam of a street light at night. That’s how University of Michigan researcher Sofia Merajver, M.D., Ph.D., describes the power of a new mathematical model that could have far-reaching impact on how scientists study cellular signaling pathways.
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Investigators at the Duke Institute for Genome Sciences and Policy have revealed the hidden properties of an on-off switch that governs cell growth.
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Molecular biologists at the University of California, San Diego have found one piece of the complex puzzle of autophagy, the process of “self-eating” performed by all eukaryotic cells -- cells with a nucleus -- to keep themselves healthy.
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An MIT team has used an engineering approach to show that complex biological systems can be studied with simple models developed by measuring what goes into and out of the system.
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New research suggests that two recently discovered genes are critically important for controlling cell survival during embryonic development.
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