UCLA scientists have linked for the first time intestinal inflammation with systemic chromosome damage in mice, a finding that may lead to the early identification and treatment of human inflammatory disorders, some of which increase risk for several types of cancer.

Chronic inflammation, which is at the root of multiple diseases, links periodontal disease to increased incidence of cardiovascular disease.

With up to half of a person’s body mass consisting of skeletal muscle, chronic inflammation of those muscles – which include those found in the limbs – can result in significant physical impairment.

A multi-center research team, led by Columbia University Medical Center, has uncovered a major contributor to the cause of stomach cancer – the second leading cause of cancer-related mortality in the world. The team described for the first time, that elevated levels of a single proinflammatory cytokine, an immune system protein called interleukin-1 beta (IL-1β), can start the progression towards stomach cancer.

Inflammation, a frontline defense against infection or disease, can help nurture skin cancer, researchers have found.

Chronic inflammation of the intestine or stomach can damage DNA, increasing the risk of cancer, MIT scientists have confirmed.

Chronic inflammation triggers bone marrow-derived blood cells to travel to the brain and fuse with a certain type of neuron up to 100 times more frequently than previously believed, according to a new study from the Stanford University School of Medicine.

More and more people in Western society are suffering from autoimmune diseases. Discovering the cause of these chronic inflammations is a first important step in the search for targeted medicines. VIB researchers connected to Ghent University and the Katholieke Universiteit Leuven joined forces and have elucidated the function of MALT1, a key player in controlling inflammatory reactions.

Most people think of hydrogen peroxide as a topical germ killer, but the medicine cabinet staple is gaining steam in the medical community as an early indicator of disease in the body.

Clinicians currently lack advance warning of acute kidney injury (AKI) for patients where kidney injury timing is unknown. Now paediatric research published in the open access journal, Critical Care, has identified a potential biomarker to predict AKI earlier than current tests, opening a vital window for prevention of this life-threatening condition.

Researchers at the University of Chicago have found an unsuspected link between the immune system and high plasma lipid levels (cholesterol and triglycerides in the blood) in mice. The finding could lead to new ways to reduce the risk of heart disease by lowering elevated lipid levels.

A complex autoimmune disease, rheumatoid arthritis (RA) is characterized by chronic inflammation and progressive joint damage. This process begins with hyperplasia, or excessive increase in size and thickness, of synovial tissue. Along with provoking cartilage and bone destruction, this abnormal tissue growth is resistant to apoptosis, the natural cell death vital to the generation of healthy new cells.