Supporting trials for FDA approved drugs often stay unpublished making physicians less informed about new drugs.

That's the question posed by leading bioethicists at Duke University Medical Center, Johns Hopkins and Georgetown Universities, who say it's time to confront the challenges that have led to the exclusion of pregnant women from important research that could positively impact maternal and fetal health.

Clinical researchers at Scottsdale Healthcare and TGen today announced the results of two clinical trials that show promise for patients battling cancer.

A representative of Australia's Stolen Generations' Alliance of Aborigines has told a Senate committee that some Aboriginal children were used for medical experimentation.

While the autorities are investigating a possible theft of personal identity information, including names, phone numbers, and in some cases social security numbers, of approximately 40,000 hospital patients at NewYork-Presbyterian Hospital/Weill Cornell Medical Center, an article from JAMA looks at Data-Sharing in clinical trials for heart disease on when and how to share patient data, and when to suspend a study.

Group-randomized trials in which participants are assigned to study arms in predetermined groups, instead of individually, infrequently met the unique statistical and design challenges required for this approach. These cancer trials may present misleading findings as a result.

Biotechnology companies are increasingly turning to developing nations as sites for clinical trials, reports Genetic Engineering and Biotechnology News (GEN). Increasing competition for clinical trial patients in the industrialized world is one of the major reasons for the offshore move, according to an article in the March 15 issue of GEN

FoxNews reports that within the next 18 months, medical researchers at The Seattle Biomedical Research Institute will be asking people in Seattle to volunteer to be exposed to the deadliest form of malaria to help them test the effectiveness of vaccine candidates.

Researchers now have a possible solution for the one in three adults who fail to take their medicines as prescribed by their doctors, as well as for everyone else who occasionally forgets: a sensor necklace that records the exact time and date when specially-designed pills are swallowed, and reminds the user if any doses are being missed.

Can a patient who agrees to participate in a safety study of a gene therapy protocol give truly informed consent and understand the risks involved when the consent forms are highly technical and the physician or institution seeking their consent has a stake in the study and its outcome?

New ways to make sure people are adequately informed about the risks and benefits of taking part in a clinical trial can be field-tested for effectiveness as vigorously as new medical treatments themselves, a study led by a Johns Hopkins bioethicist suggests.

Described as a hotspot of botanical diversity, there are more than 20,000 indigenous plant species in South Africa. Several thousand of them are used by traditional healers every day in that country for treating a range of problems from the common cold to serious diseases such as AIDS.