Mutation of a gene that helps proteins migrate in and out of the cell's genetic command center – the nucleus – puts some families at higher risk for the degenerative brain disease acute necrotizing encephalopathy (ANE).
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UCSF scientists have identified a cell population that is a primary target of the degenerative brain disease known as frontotemporal dementia, which is as common as Alzheimer's disease in patients who develop dementia before age 65.
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