diabetes

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Long-term pesticide exposure may increase risk of diabetes

Licensed pesticide applicators who used chlorinated pesticides on more than 100 days in their lifetime were at greater risk of diabetes, according to researchers from the National Institutes of Health (NIH). The associations between specific pesticides and incident diabetes ranged from a 20 percent to a 200 percent increase in risk, said the scientists with the NIH's National Institute of Environmental Health Sciences (NIEHS) and the National Cancer Institute (NCI).

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Discovery of new signal pathway important to diabetes research

Scientists at Karolinska Institutet in Sweden and Miami University have discovered that cells in the pancreas cooperate – signal – in a way hitherto unknown. The discovery can eventually be of significance to the treatment of diabetes.

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Most ongoing diabetes trials do not include outcomes

An analysis of ongoing randomized clinical trials (RCTs) in diabetes finds that only about 20 percent have as primary outcomes results that patients consider important, such as illness, pain, effect on function and death, according to a study in the June 4 issue of JAMA.

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Mouse model developed at UT Southwestern mimics hyperglycemia

UT Southwestern Medical Center researchers have genetically engineered a laboratory mouse in which pancreatic beta cells can regenerate after being induced to die. The new animal model's regenerative ability may provide future insights into improved treatments of diabetes, which affects millions of Americans.

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Diabetes doubles liver cancer risk for patients with advanced hepatitis C

Patients who have chronic hepatitis C with advanced fibrosis have twice the risk of developing liver cancer if they also have diabetes. These findings are published in the June issue of Hepatology, a journal published by John Wiley & Sons on behalf of the American Association for the Study of Liver Diseases (AASLD). The article is also available online at Wiley Interscience.

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New insights in diagnosing diabetes

In light of the 6.2 million Americans who don’t realize they have diabetes, a panel of experts examined the current criteria for screening and diagnosing the disease and found a significant need for improvement. Their conclusions and recommendations can be found in a new report accepted for publication in the Journal of Clinical Endocrinology & Metabolism (JCEM).

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Impotence Predicts Heart Problems In Diabetics

Erectile Dysfunction as a Predictor of Cardiovascular Events and Death in Diabetic Patients With Angiographically Proven Asymptomatic Coronary Artery Disease

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Novel mechanisms controlling insulin release and fat deposition discovered

Scientists at the Swedish medical university Karolinska Institutet have in two recent studies shown that a receptor called ALK7 plays important roles in the regulation of body fat deposition as well as the release of insulin from beta-cells in the pancreas. These findings have implications for the development of treatments against diabetes and obesity.

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Suspected cause of type 1 diabetes caught red-handed

Scientists at Washington University School of Medicine in St. Louis working with diabetic mice have examined in unprecedented detail the immune cells long thought to be responsible for type 1 diabetes.

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Arthritis is potential barrier to physical activity for adults with diabetes

People with diagnosed diabetes are nearly twice as likely to have arthritis, and the inactivity caused by arthritis hinders the successful management of both diseases, according to a new Morbidity and Mortality Weekly Report (MMWR) study released today by the Centers for Disease Control and Prevention (CDC).

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Toward an artificial pancreas for fighting diabetes

A specially coated metal tube, no larger than a cigarette, could be the key to developing an artificial pancreas to help millions of people with diabetes avoid insulin injections, according to an article scheduled for the May 5 issue of Chemical & Engineering News, ACS’ weekly newsmagazine.

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Studies test new approaches to islet transplantation

Researchers from 11 medical centers in the United States, Canada, Sweden, and Norway have begun testing new approaches to transplanting clusters of insulin-producing islets in adults with difficult-to-control type 1 diabetes.

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