A new study by research chemists at the University of Warwick has challenged a century old rule of pharmacology that defined how quickly key chemicals can pass across cell walls. The new observations of the Warwick researchers suggest that the real transport rates could be up to a hundred times slower than predicted by the century old "Overton's Rule".
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Researchers at Case Western Reserve University have developed a technique that has the potential to deliver cancer-fighting drugs to diseased areas within hours, as opposed to the two days it currently takes for existing delivery systems.
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In work that could at the same time impact the delivery of drugs and explain a biological mystery, MIT engineers have created the first synthetic nanoparticles that can penetrate a cell without poking a hole in its protective membrane and killing it.
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Researchers at the USC Information Sciences Institute have demonstrated a way to manufacture miniscule containers that might be used to deliver precise micro- or even nano- quantities of drugs.
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Chemical engineers at The University of Texas at Austin have discovered a new way to control the motion of fluid particles through tiny channels, potentially aiding the development of micro- and nano-scale technologies such as drug delivery devices, chemical and biological sensors, and components for miniaturized biological "lab-on-a-chip" applications.
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We encounter valves every day, whether in the water faucet, the carburetor in our car, or our bicycle tire tube. Valves are also present in the world of nanotechnology. A team of researchers headed by J. Fraser Stoddart and Jeffrey I. Zink at the University of California, Los Angeles, has now developed a new nanovalve.
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For the first time, researchers at North Carolina State University have demonstrated that microscopic "two-faced" spheres whose halves are physically or chemically different – so-called Janus particles – will move like stealthy submarines when an alternating electrical field is applied to liquid surrounding the particles.
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A new thin-film coating developed at MIT can deliver controlled drug doses to specific targets in the body following implantation, essentially serving as a “micro pharmacy.”
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In what is believed to be the first peer-reviewed study of its kind involving human subjects, researchers at the University of Kentucky College of Pharmacy and the Georgia Institute of Technology have demonstrated that patches coated on one side with microscopic needles can facilitate transdermal delivery of clinically-relevant doses of a drug that normally cannot pass through the skin.
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Using nanotechnology, scientists from UCLA and Northwestern University have developed a localized and controlled drug delivery method that is invisible to the immune system, a discovery that could provide newer and more effective treatments for cancer and other diseases.
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New polymerization technology may one day take the pain out of injections and blood draws. A team of researchers at the University of North Carolina and Laser Zentrum Hannover have recently used two-photon polymerization to create hollow needles so fine patients wouldn’t feel them piercing their skin.
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