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Healthy people and enhancement drugs

Healthy people are more willing to take drugs to enhance traits that are not fundamental to their identity.

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Men Who Shipped Marijuana to Mayor’s Home Arrested

Police in Prince George announced today that they have arrested a deliveryman and one other man believed to be behind last week’s shipping of unopened 32-pound package of marijuana to the wife of the mayor of Berwyn Heights.

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Sociologist predicts drug disasters

Americans are likely to be exposed to unacceptable side effects of FDA-approved drugs such as Vioxx in the future because of fatal flaws in the way new drugs are tested and marketed, according to research to be presented today at the annual meeting of the American Sociological Association (ASA).

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How a tiny protein senses all the communications in cell

Cells rely on calcium as a universal means of communication. For example, a sudden rush of calcium can trigger nerve cells to convey thoughts in the brain or cause a heart cell to beat. A longstanding mystery has been how cells and molecules manage to appropriately sense and respond to the variety of calcium fluctuations within cells

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First performance-enhancing drugs for exercise endurance?

While steroids can help build the bulky muscles that lend athletes and body builders power and speed, there hadn't been a drug capable of building the endurance needed to run a marathon or to ride a bike through the Alps. Now, there just might be, suggests a new study in mice reported in the journal Cell, a Cell Press publication.

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Cocaine addiction linked to voluntary drug use and cellular memory

Rats that voluntarily use cocaine show a persistent cellular memory in the brain’s reward center even after several months of abstinence from the drug, while their involuntary counterparts had no such memory, according to a new study by researchers at the University of California, San Francisco.

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NIST trumps clumps: Making biologic drugs safer

Scientists at the National Institute of Standards and Technology (NIST) have developed a technique to measure the formation of clumps of proteins in protein-based pharmaceuticals. This first systematic study clarifies the conditions under which scientists can be assured that their instruments are faithfully measuring the formation of protein aggregates, a major concern because of its impact on quality control and safety in biologic drug manufacturing.

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Screening of tiny chemical fragments may pay big dividends in drug discovery

Scientists who develop new drugs are closely following the progress through clinical trials of a cache of drugs developed with counter-intuitive strategy that defies conventional wisdom, according to an article scheduled for the July 21 issue of Chemical & Engineering News.

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Discovery first step to new therapies

In an Australian first, scientists at Sydney's Centenary Institute have mapped the anatomy of a membrane protein. This exciting discovery has the potential to turn the way we discover new drugs on its head and reduce the development time for new treatments.

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Scientists predict new uses for existing drugs from their side effects

Researchers from the European Molecular Biology Laboratory (EMBL) discovered a new way to make use of drugs' unwanted side effects. They developed a computational method that compares how similar the side effects of different drugs are and predicts how likely the drugs act on the same target molecule.

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News reports on novel hit-to-lead drug discovery

Biotech and pharmaceutical firms are developing a host of new technologies designed to streamline the complicated drug discovery process, reports Genetic Engineering and Biotechnology News (GEN).

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Members of consumer-driven health plans choosing less care

Consumer-driven health plans (CDHP) -- hailed since their inception in 2000 as a tool to help control costs -- are resulting in members forgoing care and discontinuing drugs to treat chronic medical problems, according to two newly published studies.

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