Researchers from Boston University School of Medicine and Harvard Medical School have found that diltiazem, a drug used in the treatment of high blood pressure, reduces cocaine cravings in a rat model. These findings will appear in the March issue of the leading medical journal Nature Neuroscience.
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MIT biologists have provoked soil-dwelling bacteria into producing a new type of antibiotic by pitting them against another strain of bacteria in a battle for survival.
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Scientists studying the cloudy emulsions produced by anise-flavored liquors such as Ouzo have discovered new molecular insights into their formation, findings that could lead to the design of better commercial emulsions used in making pharmaceuticals, food products, cosmetics and other materials.
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A drug therapy currently used to treat non-Hodgkin’s lymphoma and rheumatoid arthritis had a significant effect in treating the most common form of multiple sclerosis in a small, short-term clinical trial.
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New research by scientists at the University of North Carolina at Chapel Hill shows for the first time that an important family of proteins known to function at the cell surface also functions at a site within the cell.
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A new thin-film coating developed at MIT can deliver controlled drug doses to specific targets in the body following implantation, essentially serving as a “micro pharmacy.”
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In experiments with rats, researchers have identified the change in brain circuitry that drives development of a compulsion to seek drugs, even when that compulsion is self-destructive.
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In what is believed to be the first peer-reviewed study of its kind involving human subjects, researchers at the University of Kentucky College of Pharmacy and the Georgia Institute of Technology have demonstrated that patches coated on one side with microscopic needles can facilitate transdermal delivery of clinically-relevant doses of a drug that normally cannot pass through the skin.
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The FDA claimed that longer-lasting injectable version of Eli Lilly's schizophrenia drug, Zyprexa, appears effective, though a small number of patients experienced excessive sleepiness.
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An anti-virus drug attacks influenza A by changing the motion and structure of a proton channel necessary for the virus to infect healthy cells, according to a recently published research paper by two Iowa State University chemists.
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Guidance from an innovative computational approach could speed up the process and cut down the cost of new drug development, researchers from the University of Chicago Medical Center and Columbia University suggest in a study to be published in the February 2008 issue of Genome Research, available early online.
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