When it comes to the FOXP2 gene, humans have had most to shout about. Discoveries that mutations in this gene lead to speech defects and that the gene underwent changes around the time language evolved both implicate FOXP2 in the evolution of human language.

People who experience chronically high levels of loneliness show gene-expression patterns that differ markedly from those of people who don't feel lonely, according to a new molecular analysis in the online open access journal Genome Biology.

Scientists at MIT’s Department of Civil and Environmental Engineering and the Technion Israel Institute of Technology have for the first time recorded the entire genomic expression of both a host bacterium and an infecting virus over the eight-hour course of infection.

Dr. Judith A. Potashkin, Ph.D. and her colleagues at Rosalind Franklin University of Medicine and Science recently completed a study investigating one of the changes in gene expression that occurs when individuals take addictive drugs.

The Conaway Lab — led by Joan Conaway, Ph.D., and Ron Conaway, Ph.D., Investigators — has published findings that shed light on the role of the much-studied transcription factor YY1 in gene expression. Yong Cai, Ph.D., Research Specialist I, and Jingji Jin, Ph.D., Senior Research Associate, are the paper’s coequal first authors.

Scientists have discovered a pattern in the DNA sequence of the mouse genome that may play a fundamental part in the way DNA molecules regulate gene expression. The research, led by Emory University scientists along with colleagues at Jacobs University, Bremen, Germany, will be published in the Aug. 22 Advance Online publication of the journal Nature.

Kinase mediated phosphorylation is generally recognised as the major regulator of virtually all metabolic activities in eukaryotic cells including proliferation, gene expression, motility, vesicular transport and programmed cell death.

A pattern of gene expression might be able to identify which stage I lung cancer patients have the poorest prognosis.

An international team of researchers has published a benchmark study showing that gene expression in several animal models of Huntington’s Disease (HD) closely resembles that of human HD patients.

A consortium of researchers headed by Cincinnati Children’s Hospital Medical Center has discovered a gene expression pattern that could lead to improved diagnosis and treatment of pediatric septic shock – still a serious public health problem despite today’s potent antibiotics and pediatric intensive care units.

While most RNAs work to create, package, and transfer proteins as determined by the cell’s immediate needs, miniature pieces of RNA, called microRNAs (miRNAs) regulate gene expression. Recently, researchers from the University of Pennsylvania School of Medicine determined how miRNAs team up with a regulatory protein to halt protein production. Results of the study were published recently in Cell.

Scientists from the department of Biochemistry and Molecular Biology 1 of the University of Granada (Universidad de Granada) have proven that a high cholesterol diet causes changes in gene expression of chicken aortic smooth muscle cells at the early stages of an experimental atherosclerosis. This study associates cholesterol intake with the expression of genes codifying certain proteins, even before the disease is detected on blood vessel walls.