genomes

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New form of inherited risk of cancer

Like the subtext of a novel, the human genome sequence harbors more information than appears just in its "letters" of A, C, T and G. Since DNA is a data-packed molecule passed from generation to generation, comparing genome sequences among individuals also holds clues to ancestry.

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The beetle's genome sequenced for the first time

An international research consortium with the participation of a research team led by Professor Cornelis Grimmelikhuijzen from the Department of Biology, has sequenced the genome from the red flour beetle Tribolium castaneum.

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Washington University unveils draft sequence of corn genome

A team of scientists led by Washington University in St. Louis has begun to unlock the genetic secrets of corn, a crop vital to U.S. agriculture. The researchers have completed a working draft of the corn genome, an accomplishment that should accelerate efforts to develop better crop varieties to meet society's growing demands for food, livestock feed and fuel.

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New version of its metagenome data management and analysis system

Targeting its ever-expanding user community, the U.S. Department of Energy Joint Genome Institute (DOE JGI) has released an upgraded version of the IMG/M metagenome data management and analysis system, accessible to the public at http://img.jgi.doe.gov/m.

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Researchers decode genetics of rare photosynthetic bacterium

A bacterium that harvests far-red light by making a rare form of chlorophyll (chlorophyll d) has revealed its genetic secrets, according to a team of researchers who recently sequenced the bacteria’s genome.

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Chinese scientists join genome project

Scientists in London, Washington and Shenzhen on Tuesday jointly launched the 1,000 Genomes Project, which will involve sequencing the genomes of at least 1,000 people worldwide to create the most detailed and medically useful picture of human genetic variation yet.

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Johns Hopkins to participate in 1000 Genomes Project

Researchers at the McKusick-Nathans Institute of Genetic Medicine (IGM) at Johns Hopkins will join other national and international scientists in the 1000 Genomes Project, an ambitious effort that will involve sequencing the genomes of numerous people from around the world to create the most detailed and medically useful picture to date of human genetic variation.

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International consortium announces the 1000 Genomes Project

An international research consortium today announced the 1000 Genomes Project, an ambitious effort that will involve sequencing the genomes of at least a thousand people from around the world to create the most detailed and medically useful picture to date of human genetic variation.

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Copy number variation may stem from replication misstep

Genome rearrangements, resulting in variations in the numbers of copies of genes, occur when the cellular process that copies DNA during cell division stalls and then switches to a different genetic “template,” said researchers at Baylor College of Medicine in Houston in a report that appears today in the journal Cell.

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University of Toronto scientists map entire yeast genome

University of Toronto scientists have devised a tool to help understand and predict the state of a cell by successfully mapping all 70,000 nucleosomes in yeast. Nucleosomes wrap DNA before it is transformed into proteins and are critical indicators and regulators of a cell’s state.

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International team compares 12 fruit fly genomes

Cornell researchers have played a major role in an international scientific team that has compared the complete set of genes of 12 closely related fruit fly species. As well has having implications for human health -- from genetic adaptation to evolving immune systems - the analysis paves the way for better understanding the evolution of each species.

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Scientists complete DNA sequencing, analysis of multiple fruit fly genomes

In one of the first large-scale comparisons of multiple animal genomes, scientists at the Broad Institute of MIT and Harvard, the Computer Science and Artificial Intelligence Laboratory (CSAIL) at MIT, and many collaborating institutions, have analyzed the genomes of twelve species of the fruit fly Drosophila to reveal insights on the evolution of genes and genomes and to discern the functional elements encoded in animal DNA.

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