Adults with severe heart failure see almost three times as many Medicare providers each year compared to a typical beneficiary, according to research presented at the American Heart Association’s Scientific Sessions 2008.

At low concentrations, the toxic gas hydrogen sulfide protects the hearts of mice from heart failure, scientists at Emory University School of Medicine have found.

Taking a cue from the way drugs like Viagra put the biological brakes on a key enzyme involved in heart failure, scientists at Johns Hopkins have mapped out a key chemical step involved in blocking the enzyme.

Working out on a stationary bicycle or walking on a treadmill just 25 to 30 minutes most days of the week is enough to modestly lower risk of hospitalization or death for patients with heart failure, say researchers from Duke Clinical Research Institute (DCRI).

During heart failure the body reacts to the production of the hormone aldosterone. Too much aldosterone can stiffen and damage the muscles of the heart. Dutch researcher Luc Roumen has optimised compounds that inhibit the production of this hormone and looked at their optimum dosage. The compounds were manufactured by the companies Schering-Plough and SyMO-Chem BV and a drug patent has been applied for.

Data from 260 hospitals across the United States has led to the creation of a new method for physicians to more accurately determine the severity of heart failure in patients upon hospital admission, with a goal of reducing in-hospital mortality and more quickly identifying triage methods and treatment decisions.

Patients with advanced heart failure may be receiving implantable cardiac devices that do not help them because they are too ill to benefit from the treatment, a Saint Louis University study found.

Despite the general success of left ventricular assist devices (LVADs) used in critically ill heart failure patients, implantation of these devices often leads to increased bleeding and a need for high-volume blood transfusions during and immediately after surgery.

A genetic variation, found predominantly in African Americans, protects some people with heart failure, enabling them to live longer than expected. That’s the conclusion of a research team led by investigators at the University of Maryland School of Medicine in Baltimore and the Washington University School of Medicine in St. Louis.

About 40 percent of African-Americans have a genetic variant that can protect them after heart failure and prolong their lives, according to research conducted at Washington University School of Medicine in St. Louis and collaborating institutions.

Beta-blockers heal the heart via the brain when administered during heart failure, according to a new study by UCL (University College London). Up to now, it was thought that beta-blockers work directly on the heart, but the new study shows that the drugs may also act via the brain, suggesting that future therapies to treat cardiovascular disease could be targeting the central nervous system.

The number of elderly individuals newly diagnosed with heart failure has declined during the past ten years, but the number of those living with the condition has increased, according to a report in the February 25 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.