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Genetic variant mimics effect of heart failure medications

A genetic variation, found predominantly in African Americans, protects some people with heart failure, enabling them to live longer than expected. That’s the conclusion of a research team led by investigators at the University of Maryland School of Medicine in Baltimore and the Washington University School of Medicine in St. Louis.

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African-Americans have gene that prolongs life after heart failure

About 40 percent of African-Americans have a genetic variant that can protect them after heart failure and prolong their lives, according to research conducted at Washington University School of Medicine in St. Louis and collaborating institutions.

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Heart failure treated in the brain

Beta-blockers heal the heart via the brain when administered during heart failure, according to a new study by UCL (University College London). Up to now, it was thought that beta-blockers work directly on the heart, but the new study shows that the drugs may also act via the brain, suggesting that future therapies to treat cardiovascular disease could be targeting the central nervous system.

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More elderly Americans are living with heart failure

The number of elderly individuals newly diagnosed with heart failure has declined during the past ten years, but the number of those living with the condition has increased, according to a report in the February 25 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

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Heart failure patients benefit from nurse-led intervention

Heart failure patients are more likely to comply with important non-medication interventions, such as fluid and salt restrictions and regular weighing, when they have intensive support from a heart failure nurse and multidisciplinary team than if they do not, researchers reported at the American Heart Association’s Scientific Sessions 2007

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High blood pressure, low energy, recipe for heart failure

Many people with long-standing high blood pressure develop heart failure. But some don't. Daniel P. Kelly, M.D., and colleagues at Washington University School of Medicine in St. Louis and other institutions are trying to figure out what could explain that difference.

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New biomarker for heart failure predicts risk of death

A potential new biomarker for heart failure may be more powerful than established measures in identifying patients at increased risk for death from several causes.

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Cell death may accelerate decompensated heart failure

Autophagy, a normal process by which cells eat their own proteins to provide needed resources to the body in times of stress, may paradoxically cause harm to hearts already weakened by disease, researchers from UT Southwestern Medical Center have found.

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Clinical trial of Cardiac Resynchronization Therapy

The University of Zurich announces today an investigator initiated large-scale prospective randomized controlled clinical trial to assess the clinical impact of Cardiac Resynchronization Therapy (CRT) in heart failure patients.

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Best fitness program for patients with stable heart failure

Countless exercise programs claim to trim the thighs, abs and buttocks, but how many offer to reshape a flabby heart" According to new research, aerobic exercise does just that for patients with stable heart failure, literally turning an enlarged heart into a trimmer, more efficient organ for pumping blood throughout the body.

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Herceptin does not increase heart failure in patients

Risk of congestive heart failure in women treated with trastuzumab (Herceptin) and combination chemotherapy for early-stage breast cancer did not increase over time according to a five-year follow-up of National Surgical Adjuvant Breast and Bowel Project (NSABP) trial B-31, presented at the annual meeting of the American Society of Clinical Oncology (ASCO) in Chicago.

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How to predict mortality risk in heart failure patients?

A simple exercise test may help predict mortality risk in patients with heart failure and help doctors to better tailor treatment strategies, according to new research from Wake Forest University Baptist Medical Center.

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