Researchers at Emory University and Georgia Institute of Technology have developed tiny polymer beads that can slowly release anti-inflammatory drugs and break down into non-toxic components.
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Geron Corporation today reported its scientists and collaborators have demonstrated that human embryonic stem cell (hESC)-derived cardiomyocytes improve heart function when transplanted after myocardial infarction.
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When human hearts are injured, as during a heart attack, healthy tissue normally can't regrow. Researchers now demonstrate in rats that a sponge-like patch, soaked in a compound called periostin and placed over the injury, can not only get heart cells to begin dividing and making copies of themselves again, but also improves heart function. Their findings appear in the July 15 online edition of Nature Medicine.
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Researchers at the University of Alberta have shown that Viagra, the popular drug prescribed for erectile dysfunction, can improve heart function and potentially save the lives of people with specific heart problems.
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Funded by the MBF Foundation, the second phase of the project will test whether using the G-SCF hormone to stimulate the release of blood vessel-forming stem cells can alleviate the condition, improve heart function and increase quality of life for people with severe heart disease.
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