hormone therapy

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Drug target for treatment-resistant prostate cancer

Scientists at Jefferson’s Kimmel Cancer Center in Philadelphia have found that a signaling protein that is key to prostate cancer cell growth is turned on in nearly all recurrent prostate cancers that are resistant to hormone therapy.

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Hormone therapy boosts sexual interest

Hormone therapy in early post-menopause increases sexual interest, but does not improve memory, according to a study in the Sept. 25 issue of the journal Neurology.

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Hormone therapy in early post-menopause has no effect on memory

Hormone therapy taken in the first few years after menopause does not appear to affect a woman’s memory, but may lead to increased sexual interest, according to a study published in the September 25, 2007, issue of Neurology, the medical journal of the American Academy of Neurology.

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Women are less aware of landmark hormone therapy study

Despite the huge publicity generated by a 2002 study on the potential dangers of hormone therapy for postmenopausal women, new research from the Stanford University School of Medicine found that only 29 percent of women surveyed knew about the study two years later.

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Microarray provides genomic guides to breast cancer treatment

Three genomic tests separately predict the likelihood that a patient's breast cancer will reoccur after surgery without additional treatment, and the cancer's vulnerability to chemotherapy or hormone therapy, researchers at The University of Texas M. D. Anderson Cancer Center report at the first American Society of Clinical Oncology ASCO Breast Cancer Symposium Sept. 7-8 in San Francisco.

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Identifying markers for menopausal women at risk for deadly blood clot

In women, hormone therapy is a risk factor for venous thrombosis, a blood clot forming deep inside the vein. Despite the fact that the disorder is rare, it increases exponentially during menopause and can be deadly. The hormone trials conducted thus far, focusing on proteins in blood coagulation, have not yet led to a risk profile, thereby precluding identification of women at risk.

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Breast cancer and hormone therapy

The medical community has been debating for many years whether, and to what extent, postmenopausal hormone therapy (HT) use is associated with a higher risk of breast cancer, says Professor Amos Pines, President of the International Menopause Society.

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Monkey studies parallel WHI findings, point to importance

Studies in female monkeys helped raise important questions about hormone therapy that were addressed in a Women’s Health Initiative study reported last week in the New England Journal of Medicine.

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Estrogen therapy in postmenopausal women linked to less plaque in arteries

New results from a substudy of the Women's Health Initiative (WHI) Estrogen-Alone Trial show that younger postmenopausal women who take estrogen-alone hormone therapy have significantly less buildup of calcium plaque in their arteries compared to their peers who did not take hormone therapy. Coronary artery calcium is considered a marker for future risk of coronary artery disease.

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Hormone therapy offers new hope for ovarian cancer patients

Researchers at the University of Edinburgh have shown that hormone therapy can extend life in ovarian cancer patients, giving women a new alternative to chemotherapy.

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Treatment for early prostate cancer associated with type of specialist seen

A new study analyzing men with localized prostate cancer shows that the specialty of the physician they see can influence the type of therapy they ultimately receive.

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COX Inhibitors Weaken Protective Qualities of Estrogen Hormone Therapy

Researchers from the University of Pennsylvania School of Medicine found in a database study of women heart patients that COX inhibitors such as traditional nonsteroidal anti-inflammatory drugs (NSAIDs) may undermine any purported protection against heart disease in participants taking estrogen therapy. The results were described this week in PLoS Medicine.

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