University of Florida researchers have identified a drug compound that dramatically lowers blood pressure, improves heart function and — in a remarkable finding — prevents damage to the heart and kidneys in rats with persistent hypertension.

The research team found that the hypertension drugs diltiazem and verapamil increased the overall function of mutant lysosomal enzymes associated with the conditions Gaucher disease, ѓС-mannosidosis, and type IIIA mucopolysaccharidosis in patient-derived cell lines.

Patients with hypertension and certain gene variations experienced varying results with some blood pressure medications, suggesting matching a patient’s genotype with certain hypertension medications could result in more favorable outcomes, according to a study in the January 23 issue of JAMA.

A new study has identified commonly prescribed drugs for the treatment of hypertension may be capable of preventing Alzheimer's disease and cognitive deterioration.

About half of California adults diagnosed with high blood pressure, or hypertension, do not take medication to lower it, researchers reported today at the American Heart Association’s 61st Annual Fall Conference of the Council for High Blood Pressure Research.

Patients with high blood pressure respond very differently to antihypertensive medication, making treatment selection tricky for physicians. But new research published in the online open access journal, BMC Medical Genetics, pinpoints a number of gene-drug interactions that could allow medication to be tailored to individual patients based on their genetics.

Hispanic women with hypertension and coronary artery disease respond better to drug regimens aimed at controlling high blood pressure than non-Hispanic white women, University of Florida researchers report.

Some high blood pressure medicines may help protect older adults from declines in memory and other cognitive function, according to new research from Wake Forest University School of Medicine, reported today at the annual meeting of the American Geriatrics Society in Seattle.