The lupus-suppressing action is the result of what is known as a nonsense mutation of the Coronin-1A gene (Coro1a) required for the development of the disease. A nonsense mutation causes the gene to produce proteins that no longer function.

Good patient information is essential for choosing the best treatment for the kidney disease lupus nephritis. Dutch researcher Cecile Grootscholten concludes this following her doctoral research into two methods for treating lupus nephritis. She did not demonstrate any major differences but both treatments have pros and cons.