Men and their physicians need not hesitate to use a drug proven effective in preventing prostate cancer out of concern that it is likely to cause sexual dysfunction, say authors of a study conducted by the Southwest Oncology Group.

For prostate cancer patients whose tumors have continued to grow despite medical or surgical castration, a new drug candidate that inhibits production of male hormones anywhere in the body is showing promise in early trials.

Production of a protein that promotes inflammation appears to be linked to the higher incidence of liver cancer in men than in women, researchers at the University of California, San Diego (UCSD) School of Medicine have determined in mouse studies.

Artificially replicating the male genome could help men with very low sperm counts become fathers, a scientist told the 23rd annual conference of the European Society of Human Reproduction and Embryology (Tuesday 3 July).

A factor in immune cells regulates human semen and seems to determine whether a man will be fertile, according to a new study.

The prognosis for systemic lupus erythematosus (SLE), an autoimmune disease that mainly affects women in their reproductive years, has improved recently, prompting a shift toward improving quality of life. For men with SLE, concerns have been raised about their future fertility.

Two new studies suggest older men and women taking selective serotonin reuptake inhibitors, a class of antidepressants that includes Prozac, Paxil and Zoloft, are prone to increased bone loss.

A novel method of drug delivery to inhibit the growth of prostate cancer cells has been developed by a doctoral candidate in pharmacy at the Hebrew University of Jerusalem.

In new academic research published today in the online, open-access, peer-reviewed scientific journal PLoS ONE, male circumcision is found to be much less important as a deterrent to the global AIDS pandemic than previously thought.

The researchers participated in the Agency's Berlin Bed-Rest Study, monitoring 20 healthy, young men who spent 56 days lying in bed. Lead researcher Dr Daniel Belavy said prolonged inactivity shrunk the deep muscles that protected the mens' backs.

The number of tumor cells circulating in the bloodstream of patients with metastatic, hormone-resistant, prostate cancer can predict how they will do with chemotherapy, according to results of an international trial. The findings, if backed by larger studies, could have important implications for designing personalized treatments for this very dangerous type of prostate cancer, the researchers say.

Genetic variations may help explain why some men with depression develop suicidal thoughts and behaviors after they begin taking antidepressant medications, while most do not, according to a report in the June issue of Archives of General Psychiatry, one of the JAMA/Archives journals.