Mutant genes

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Mutant host cell protein sequesters critical HIV-1 element

Scientists have identified a new way to inhibit a molecule that is critical for HIV pathogenesis.

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New mouse mutant contains clue to progressive hearing loss

Researchers have defined a mutation in the mouse genome that mimics progressive hearing loss in humans. A team from the Wellcome Trust Sanger Institute in Cambridge, UK, working with colleagues in Munich and Padua, found that mice carrying a mutation called Oblivion displayed problems with the function of hair cells in the inner ear, occurring before clear physical effects are seen.

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Technique Opens New Horizons For Scientists Seeking Disease-Related Genes

Scientists at Cold Spring Harbor Laboratory (CSHL) have developed a new means of extracting and interpreting data from the human genome that is more powerful and more economical than methods currently employed.

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Mutant gene shatters nerves

If you bend a knee or an elbow, the nerves in your limbs stretch but do not break. A University of Utah study suggests why: A gene produces a springy protein that keeps nerve cells flexible. When the gene was disabled in tiny nematode worms, their nerve cells literally broke.

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