Scientists funded by the Biotechnology and Biological Sciences Research Council (BBSRC) have uncovered what happens to biomimetic nanoparticles when they enter human cells. They found that the important proteins that make up the outer layer of these nanoparticles are degraded by an enzyme called cathepsin L. Scientists now have to take this phenomenon into account and overcome this process to ensure the exciting field of nanomedicine can progress. The research is published today in ACS Nano.

A revolutionary new protein stabilisation technique has been developed by scientists funded by the Biotechnology and Biological Sciences Research Council (BBSRC) which could lead to 30 per cent more proteins being available as potential targets for drug development - opening up exciting possibilities in drug discovery.

Scientists and engineers at UC Santa Barbara and other researchers have developed a nanoparticle that can attack plaque –– a major cause of cardiovascular disease. The new development is described in a recent issue of the Proceedings of the National Academy of Sciences.

Arizona State University researchers Hao Yan and Yan Liu imagine and assemble intricate structures on a scale almost unfathomably small. Their medium is the double-helical DNA molecule, a versatile building material offering near limitless construction potential.

Using tiny gold particles and infrared light, MIT researchers have developed a drug-delivery system that allows multiple drugs to be released in a controlled fashion.

Deriving plentiful electricity from sunlight at a modest cost is a challenge with immense implications for energy, technology, and climate policy. A paper in a special energy issue of Optics Express, the Optical Society's (OSA) open-access journal, describes a relatively new approach to solar cells: lacing them with nanoscopic metal particles.

Researchers have developed a new generation of microscopic particles for molecular imaging, constituting one of the first promising nanoparticle platforms that may be readily adapted for tumor targeting and treatment in the clinic.

Researchers at the University of Delaware have provided what is believed to be the first experimental evidence that plants can take up nanoparticles and accumulate them in their tissues.

Because they are riddled with defects, bulk crystalline materials never achieve their ideal strength; nanocrystals, on the other hand, are so small there’s no room for defects. (“Nano” is short for nanometer, a billionth of a meter.)

Novel nanoparticles being tested at the National Institute of Standards and Technology (NIST) have researchers seeing stars. In a recent paper,* NIST scientists used surface-enhanced Raman spectroscopy (SERS) to demonstrate that gold nanostars exhibit optical qualities that make them superior for chemical and biological sensing and imaging.

Purdue University researchers have developed a method of using nanoparticles to deliver treatments to injured brain and spinal cord cells.

Gold nanoparticles are everywhere. They are used in cancer treatments, automobile sensors, cell phones, blood sugar monitors and hydrogen gas production. However, until recently, scientists couldn't create the nanoparticles without producing synthetic chemicals that had negative impacts on the environment.