neurodevelopmental disorders

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Toward long-sought saliva test for autism

Researchers in Italy are reporting discovery of abnormal proteins in the saliva of autism patients that could eventually provide a clue for the molecular basis of this severe developmental disorder and could be used as a biomarker for a subgroup of patients with autism spectrum disorders (ASD). Their study is in the January 2 issue of ACS' Journal of Proteome Research, a monthly publication.

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Rare genetic disorder gives clues to autism, epilepsy, mental retardation

A rare genetic disorder called tuberous sclerosis complex (TSC) is yielding insight into a possible cause of some neurodevelopmental disorders: structural abnormalities in neurons, or brain cells.

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Benefits of closing plants on early childhood neurodevelopment

Closing coal-fired power plants can have a direct, positive impact on children's cognitive development and health according to a study released by the Columbia Center for Children's Environmental Health (CCCEH) at Columbia University's Mailman School of Public Health.

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The first autism disease genes

The autistic disorder, a neurodevelopmental disease first described in 1943, represents a challenge for treatment and a puzzle for research. Alongside Asperger syndrome, a milder form of the disorder, autism is classified in the continuum of various Autism Spectrum Disorders (ASD), all of which are characterized by deficits in language, social interaction, and a strangely restricted and repetitive behaviour (stereotypy).

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The Rett gene, rogue activator

In 1999, when Dr. Huda Zoghbi and her Baylor College of Medicine colleagues identified a mutation of the gene MeCP2 as the culprit in Rett syndrome, a neurodevelopmental disorder, the discovery was only the prelude to understanding a symphony of neurological missteps.

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Jumping gene may contribute to premature aging syndrome

Scientists have identified a fusion protein that may contribute to Cockayne syndrome, a devastating disease characterized by developmental defects, neurodegeneration, severe wasting, and premature aging. The study is described in an article published March 21 in the open-access journal PLoS Genetics.

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Prenatal exposure to maternal antibodies linked to autistic behaviors in offspring

New research from the UC Davis M.I.N.D. Institute shows that an interaction between fetal brain cells and maternal antibodies could be linked with the repetitive behavior — also called stereotypies — that is characteristic of autism.

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Lilly Stalling on Zyprexa Payouts

A big hurdle with the Zyprexa issue is Lilly's credibility over their continuous PR on how they are going to pay out $1.2 billion in damages.

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New protein implicated in autism

Autism is a common neurodevelopmental disorder characterized by severely impaired social, communicative, and behavioral functions. It is thought that genetic make-up predisposes an individual to autism, and several genes have been associated with the development of autism.

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