neurological disorders

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Scientists Identify Chemical that Triggers Parkinson’s Disease

Researchers at the Saint Louis University School of Medicine have discovered the key brain chemical that causes Parkinson's disease - a breakthrough finding that could pave the way for new, far more effective therapies to treat one of the most common and debilitating neurological disorders.

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Antibody leads to repair of myelin sheath

Mayo Clinic researchers have found that a human antibody administered in a single low dose in laboratory mouse models can repair myelin, the insulating covering of nerves that when damaged can lead to multiple sclerosis and other disorders of the central nervous system.

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Gene loss leads to protein splicing

Researchers at Mayo Clinic in Jacksonville have discovered how loss of a gene can lead to accumulation of toxic proteins in the brain, resulting in a common dementia, and they say this mechanism may be important in a number of age-related neurological disorders.

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Molecule that protects from neuronal disorders

Researchers discover a protein required for the normal development of the cerebral cortex and to prevent defects associated with mental retardation

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Proteins involved in new neurodegenerative syndrome

The interplay of two proteins that bind to messenger RNA, a molecule that mediates translation of the information encoded in genes into proteins, triggers the appearance of fragile X-associated tremor/ataxia syndrome (FTAX), a late-life disorder associated with the gene that causes fragile X syndrome in children, said researchers from Baylor College of Medicine in Houston and Emory University School of Medicine in a report that appears today in the journal Neuron.

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New diagnostic test for detecting infection in prosthetic joints

Researchers have reported new insight into the pathology underlying a recently identified neurological disorder that strikes middle-aged adults that is caused by alterations in the same gene that causes fragile X syndrome.

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Deep into machinery of adult fragile X

Researchers have reported new insight into the pathology underlying a recently identified neurological disorder that strikes middle-aged adults that is caused by alterations in the same gene that causes fragile X syndrome.

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New treatment boosts muscle function in myasthenia gravis

A new type of treatment significantly reduces the severity of muscle weakness in myasthenia gravis (MG), giving hope for a new class of drugs to treat neurological disorders, according to a study published in the August 14, 2007, issue of Neurology®, the medical journal of the American Academy of Neurology.

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Independent brain networks control human walking

In a study published in the August issue of Nature Neuroscience, researchers at the Kennedy Krieger Institute in Baltimore, Maryland found that there are separate adaptable networks controlling each leg and there are also separate networks controlling leg movements, e.g., forward or backward walking.

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Mild stress in womb may worsen risk of cerebral palsy

Chronic mild stress in pregnant mothers may increase the risk that their offspring will develop cerebral palsy—a group of neurological disorders marked by physical disability—according to new research in mice. The results may be the first to demonstrate such effects of stress on animals in the womb.

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New study on genetic roots of Alzheimer's

Scientists have known for more than a decade that individuals with a certain gene are at higher risk for developing Alzheimer's disease. Now a new study helps explain why this is so.

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Restless legs syndrome increases risk of heart disease

People with restless legs syndrome (RLS), especially the elderly, may be at an increased risk of developing cardiovascular disease, according to a study published in the April 10, 2007, issue of Neurology®, the scientific journal of the American Academy of Neurology.

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