A new study published by researchers at the UCLA School of Dentistry substantiates the effectiveness of measuring the microRNAs present in saliva to detect oral squamous cell carcinoma. Like hall monitors in an elementary school, microRNAs are the molecules produced by cells that simultaneously asses the behavior of multiple genes and control their activity.

Human calmodulin-like protein (CLP) is found in many cell types including breast, thyroid, prostate, kidney, and skin. The protein can regulate many cell activities and has a highly specific expression.

A call to explore a broader use of HPV (human papillomavirus) vaccines and the validation of a simple oral screening test for HPV-caused oral cancers are reported in two studies by a Johns Hopkins Kimmel Cancer Center investigator.

Clinicians could detect oral squamous cell carcinoma, a form of oral cancer, using a simple test that detects proteins in saliva, according to a report in the October 1, 2008, issue of Clinical Cancer Research, a journal of the American Association for Cancer Research. This work was led by David T. Wong, D.M.D., D.M.Sc., professor and associate dean for research, at the University of California, Los Angeles School of Dentistry.

Three new studies published in the June 2008 edition of Otolaryngology – Head and Neck Surgery focus on what role gender plays in the prognosis of oral tongue cancer, chronic ear infections in children, and the success rates of hearing aid implants in the elderly.

Researchers from the Dental Institute and the Nutritional Science Research Division, led by Professors Saman Warnakulasuriya and Victor R Preedy have published new research findings which herald a significant advance in understanding how alcohol may cause oral (mouth) cancer.

Nutrients taken from avocados are able to thwart oral cancer cells, killing some and preventing pre-cancerous cells from developing into actual cancers, according to researchers at Ohio State University.

The Centers for Disease Control report that nearly 25 million women are infected with some form of the Human Papilloma Virus (HPV). Of those, more than three million are thought to have one of the four strains known to cause cases of cervical cancer and genital warts.

More than 92 percent of Illinois dentists provide oral cancer examinations for their patients, but many are not performing the procedures thoroughly or at optimum intervals, according to a new University of Illinois at Chicago study.

Men with chronic gum disease may have an increased risk of tongue cancer, regardless of whether they smoke, according to a report in the May issue of Archives of Otolaryngology-Head & Neck Surgery, one of the JAMA/Archives journals.

Oral cancer is diagnosed in more than 30,000 individuals in the US annually, claiming 10,000 lives each year. Early detection remains the best way to ensure patient survival and quality of life. Today, during the 85th General Session of the International Association for Dental Research, scientists from the University of California-Irvine present two novel, non-invasive, ultra-fast imaging approaches to oral cancer detection, diagnostic screening, and mapping.

Today, during the 85th General Session of the International Association for Dental Research, scientists are reporting that the use of saliva for clinical detection of major human diseases is only a few years away. Intense research is ongoing to discover diagnostic saliva biomarkers. A necessary prerequisite is to know, in a comprehensive manner, the informative biomarkers in saliva: the diagnostic alphabets.