A soft pancreatic texture with a narrow pancreatic ductal size creates a high risk for the development of a pancreatic fistula after pancreaticoduodenectomy, often leading to death. Several methods have been advocated to reduce the occurrence of leakage, but the best technique is still a subject of debate.

Studies have shown that the best opportunity for long-term survival in patients with pancreatic cancer (PC) is with surgical removal of the tumor during pancreaticoduodenectomy (PD).