The body of Ashley "AJ" Jewell will be exhumed for a second autopsy. The Fulton DA has agreed to the exhumation due to the findings of the first autopsy.

Pediatric researchers have resolved an apparent contradiction in the field of prenatal cell transplantation— a medical approach that holds future promise in correcting sickle cell disease and other serious congenital blood disorders. In a new study in animals, the researchers showed that the mother's immune response interferes with the offspring's earlier ability to tolerate transplanted donor cells.

Researchers have identified a gene that directly affects the production of a form of hemoglobin that is instrumental in modifying the severity of the inherited blood disorders sickle cell disease and thalassemia.

Using a harmless virus to insert a corrective gene into mouse blood cells, scientists at St. Jude Children's Research Hospital have alleviated sickle cell disease pathology. In their studies, the researchers found that the treated mice showed essentially no difference from normal mice.

A new study finds that youth populations with sickle cell disease (SCD) are receiving inadequate healthcare, and thus may fail to benefit from scientific advances. The study, published in Pediatric Blood & Cancer, finds that the patients, mostly African Americans, often lack insurance or access to specialized sickle cell centers for treatment.

Although sickle cell disease is a single-gene disorder, its symptoms are highly variable. In a study published online July 14 by the Proceedings of the National Academy of Sciences, scientists at Children's Hospital Boston and the Dana Farber Cancer Institute (DFCI), in collaboration with the Broad Institute of MIT and Harvard, report five gene variants that could potentially be helpful in predicting sickle cell disease severity, perhaps even leading to better treatment approaches in the future.

Children with sickle cell disease (SCD) have a significantly sharper decline in lung function with age when compared to other children of the same race and age. Furthermore, that loss of function appears to be linked to a restrictive rather than obstructive pattern, contrary to previous research that has focused on obstructive or asthma-like patterns in loss of lung function with sickle cell disease.

It’s long been known that patients with sickle cell disease have malformed, “sickle-shaped” red blood cells – which are normally disc-shaped – that can cause sudden painful episodes when they block small blood vessels.

Researchers are identifying innovative therapeutics for sickle cell anemia that focus on specific factors in the disease's progression, such as the important role of hydration of the red blood cells.

A group of children who have sickle cell disease and who experience silent strokes showed some relief from the silent strokes with blood transfusion therapy, researchers at Washington University School of Medicine in St. Louis have found.

Sickle cell disease (SCD) is an inherited blood disorder caused by a genetic mutation that leads to the generation of a mutant form of the beta-globin chain of hemoglobin (Hb).

An intravenous “blood thinner” widely used in patients with acute coronary syndromes and during coronary artery stent placement appears to be safe in patients with sickle cell disease and may have beneficial anti-inflammatory effects, a small study at the University of North Carolina at Chapel Hill School of Medicine has found.