Researchers at the Johns Hopkins School of Medicine have discovered how one antioxidant protein controls the activity of another protein, critical for the development of spinal cord neurons. The research, publishing this week in Cell, describes a never-before known mechanism of protein control.

The novel design of a deep muscle along the spinal column called the multifidus muscle may in fact be key to spinal support and a healthy back, according to researchers at the University of California, San Diego School of Medicine.

Multiple sclerosis is a disease caused by the loss of the myelinated sheath surrounding the nerve fibers of the spinal cord. Therapeutic hope for curing multiple sclerosis and other demyelinating diseases has included the possibility that stem cell transplants could help remyelinate the spinal cord.

According to the AANS, Chiari malformation can be difficult to diagnose because the symptoms mimic several other conditions, and as a result, patients are often told that there is no physical problem. Chiari malformation is indeed a physical condition and getting a proper diagnosis is the first step on the path to finding treatment that may provide hope and relief.

A detergent solution developed at The University of Texas at Austin that treats donor nerve grafts to circumvent an immune rejection response has been used to create acellular nerve grafts now used successfully in hospitals around the country. Research also shows early promise of the detergent solution having possible applications in spinal cord repair.

It is not uncommon to find tissue that normally lines the stomach in locations outside of the digestive tract. This "heterotopic" gastric tissue has been identified in such diverse locations as the scrotum, the gall bladder, and the spinal cord.

Stowers Institute researchers Karen Staehling-Hampton, Ph.D., Managing Director of Molecular Biology, and Olivier Pourquie, Ph.D., Investigator, collaborated with colleagues from around the world to show that genes known to cause spinal mutations in chick and mouse model systems also play an important role in human patients with congenital vertebral abnormalities.

Mayo Clinic has clarified the methods of diagnosis and optimal management of a rare and little-understood blood vessel disease of the brain and spinal cord that often leads to stroke or death. Primary central nervous system vasculitis (PCNSV) can best be identified through a combination of diagnostic techniques consisting of angiography (imaging the cerebral arteries), brain biopsy and other laboratory studies.

Science of tomorrow promises to alleviate suffering from intractable ailments of today