A new study by researchers at Rhode Island Hospital provides much-needed insight into the molecular mechanisms that cause arrythmia, or irregular heartbeat, and how it triggers sudden cardiac death, one of the nation’s leading killers. Their findings, published online in the Journal of Clinical Investigation, could pave the way for the development of new, genetically-targeted therapies to treat and prevent fatal arrythmias.

Women whose kidneys are poor at filtering impurities from the blood are at heightened risk of sudden cardiac death, according to a report published in Hypertension: Journal of the American Heart Association.

David Callans, MD, a professor of cardiovascular medicine at the University of Pennsylvania School of Medicine, will be available to comment on the New England Journal of Medicine study on the use of automated external defibrillators (AEDs) for sudden cardiac arrests that occur in the home.

A recently approved angina drug may also represent a powerful new treatment for a rare hereditary syndrome that places teens at risk for sudden cardiac death, according to research presented to today at the 57th Annual Scientific Sessions of the American College of Cardiology (ACC) in Chicago.

A study appearing in this week’s New England Journal of Medicine confirms that a combination of gene variants previously associated with cholesterol levels does reflect patients’ cholesterol levels and can signify increased risk of heart attack, stroke or sudden cardiac death.

Methadone is a possible cause of sudden cardiac death even when it isn’t overdosed but is taken at therapeutic levels primarily for relief of chronic pain or drug addiction withdrawal, a new study by Oregon Health & Science University researchers suggests.

Every year, 300,000 Americans die suddenly when, out of the blue, a “storm” of electrical activity arises within their heart muscle – so violent and so abrupt that their hearts just stop beating. These tragic and dramatic “sudden cardiac deaths” strike people young and old, often without warning.

Among Medicare patients, men are about 2-3 times more likely than women to receive an implantable cardioverter-defibrillator for the prevention of sudden cardiac death, according to a study in the October 3 issue of JAMA.

High-risk patients with hypertrophic cardiomyopathy appear to have reduced risk of sudden cardiac death with an implantable cardioverter-defibrillator that terminates dangerous heart rhythm disorders, according to a study in the July 25 issue of JAMA.

Statin drugs, known primarily for their ability to lower cholesterol, also may reduce the overactive sympathetic nervous system response that contributes to the worsening of heart failure and increases the risk of sudden cardiac death, two University of Missouri-Columbia researchers have found. Heart failure is the leading cause of morbidity and mortality in the United States.