QRS duration (QRSd) is one of several measures of heart function recorded during a routine electrocardiogram (ECG). It is a composite of waves showing the length of time it takes for an electrical signal to get all the way through the pumping chambers of the heart. Prolonged QRSd is a sign of an abnormal electrical system of the heart and is often found when the heart isn't pumping efficiently.

Building on these findings, the Helmholtz scientists and their clinical partners want to obtain further insights into the pathogenesic mechanisms of the disease and gain perspectives for early diagnosis and therapy. The results of the genome-wide study have been published online in the journal Nature Genetics.

Before flying off the handle the next time someone cuts you off in traffic, consider the latest research from Yale School of Medicine researchers that links changes brought on by anger or other strong emotions to future arrhythmias and sudden cardiac arrests, which are blamed for 400,000 deaths annually.

In about 10% of cases, sudden cardiac death (SCD) in young people is due to a cardiac gene defect.

The risk of sudden cardiac death following a heart attack has declined significantly in the past 30 years, although patients appear to be at elevated risk for sudden cardiac death for the first month after having a heart attack, after which time their risk decreases unless they develop heart failure, according to a study in the November 5 issue of JAMA.

A new study by researchers at Rhode Island Hospital provides much-needed insight into the molecular mechanisms that cause arrythmia, or irregular heartbeat, and how it triggers sudden cardiac death, one of the nation’s leading killers. Their findings, published online in the Journal of Clinical Investigation, could pave the way for the development of new, genetically-targeted therapies to treat and prevent fatal arrythmias.

Women whose kidneys are poor at filtering impurities from the blood are at heightened risk of sudden cardiac death, according to a report published in Hypertension: Journal of the American Heart Association.

David Callans, MD, a professor of cardiovascular medicine at the University of Pennsylvania School of Medicine, will be available to comment on the New England Journal of Medicine study on the use of automated external defibrillators (AEDs) for sudden cardiac arrests that occur in the home.

A recently approved angina drug may also represent a powerful new treatment for a rare hereditary syndrome that places teens at risk for sudden cardiac death, according to research presented to today at the 57th Annual Scientific Sessions of the American College of Cardiology (ACC) in Chicago.

A study appearing in this week’s New England Journal of Medicine confirms that a combination of gene variants previously associated with cholesterol levels does reflect patients’ cholesterol levels and can signify increased risk of heart attack, stroke or sudden cardiac death.

Methadone is a possible cause of sudden cardiac death even when it isn’t overdosed but is taken at therapeutic levels primarily for relief of chronic pain or drug addiction withdrawal, a new study by Oregon Health & Science University researchers suggests.

Every year, 300,000 Americans die suddenly when, out of the blue, a “storm” of electrical activity arises within their heart muscle – so violent and so abrupt that their hearts just stop beating. These tragic and dramatic “sudden cardiac deaths” strike people young and old, often without warning.